Isolation and characterization of a fluorescent material in bovine achilles tendon collagen

A fluorescent material in bovine achilles tendon collagen was isolated and characterized by ultraviolet spectroscopy, fluorescence spectroscopy and nmr spectroscopy. The data suggest that the compound is a 3-hydroxypyridinium derivative with three amino acid side chains. The name “pyridinoline” is p...

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Veröffentlicht in:	Biochemical and biophysical research communications 1977-06, Vol.76 (4), p.1124-1129
Hauptverfasser:	Fujimoto, Daisaburo, Akiba, Kin-ya, Nakamura, Nobuo
Format:	Artikel
Sprache:	eng
Schlagworte:	Achilles Tendon Animals Cattle Collagen - analysis Magnetic Resonance Spectroscopy Molecular Weight Pyridinium Compounds - analysis Spectrometry, Fluorescence Spectrophotometry, Ultraviolet
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Zusammenfassung:	A fluorescent material in bovine achilles tendon collagen was isolated and characterized by ultraviolet spectroscopy, fluorescence spectroscopy and nmr spectroscopy. The data suggest that the compound is a 3-hydroxypyridinium derivative with three amino acid side chains. The name “pyridinoline” is proposed. Pyridinoline is a novel type crosslink of collagen.
ISSN:	0006-291X 1090-2104
DOI:	10.1016/0006-291X(77)90972-X