Further Evidence of a High Degree of Genetic Homology Between H. influenzae and H. aegyptius.
Summary DNA-mediated transformation to novobiocin resistance has been conferred in sensitive H. aegyptius populations. A comparison of the frequency of this event induced by DNA of heterologous source (resistant Rd H. influenzae) and by DNA of homologous source (resistant H. aegyptius) supports the...
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| Veröffentlicht in: | Experimental biology and medicine (Maywood, N.J.) N.J.), 1965-03, Vol.118 (3), p.671-679 |
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| container_issue | 3 |
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| container_title | Experimental biology and medicine (Maywood, N.J.) |
| container_volume | 118 |
| creator | Leidy, Grace Jaffee, Iris Alexander, Hattie E. |
| description | Summary
DNA-mediated transformation to novobiocin resistance has been conferred in sensitive H. aegyptius populations. A comparison of the frequency of this event induced by DNA of heterologous source (resistant Rd H. influenzae) and by DNA of homologous source (resistant H. aegyptius) supports the earlier report(3) which suggested a high degree of genetic homology between H. aegyptius and H. influenzae. The data suggest that a genetic factor (s) inherent in the receptor population influences the level of novobiocin resistance conferred by a given DNA. The genetic factors controlling streptomycin and novobiocin resistance have been demonstrated to be linked in H. aegyptius. |
| doi_str_mv | 10.3181/00379727-118-29935 |
| format | Article |
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DNA-mediated transformation to novobiocin resistance has been conferred in sensitive H. aegyptius populations. A comparison of the frequency of this event induced by DNA of heterologous source (resistant Rd H. influenzae) and by DNA of homologous source (resistant H. aegyptius) supports the earlier report(3) which suggested a high degree of genetic homology between H. aegyptius and H. influenzae. The data suggest that a genetic factor (s) inherent in the receptor population influences the level of novobiocin resistance conferred by a given DNA. The genetic factors controlling streptomycin and novobiocin resistance have been demonstrated to be linked in H. aegyptius.</description><identifier>ISSN: 0037-9727</identifier><identifier>ISSN: 1535-3702</identifier><identifier>EISSN: 1535-3699</identifier><identifier>DOI: 10.3181/00379727-118-29935</identifier><identifier>PMID: 14264525</identifier><language>eng</language><publisher>London, England: SAGE Publications</publisher><subject>DNA ; DNA, Bacterial ; Drug Resistance ; Drug Resistance, Microbial ; Genetics ; Haemophilus ; Haemophilus influenzae ; Mutation ; Novobiocin ; Old Medline ; Streptomycin</subject><ispartof>Experimental biology and medicine (Maywood, N.J.), 1965-03, Vol.118 (3), p.671-679</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c341t-c8635310c05da25e9cbd56416dfc543fb78748e607ba402b33f0f857ca3eb3a73</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,778,782,27911,27912</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/14264525$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Leidy, Grace</creatorcontrib><creatorcontrib>Jaffee, Iris</creatorcontrib><creatorcontrib>Alexander, Hattie E.</creatorcontrib><title>Further Evidence of a High Degree of Genetic Homology Between H. influenzae and H. aegyptius.</title><title>Experimental biology and medicine (Maywood, N.J.)</title><addtitle>Proc Soc Exp Biol Med</addtitle><description>Summary
DNA-mediated transformation to novobiocin resistance has been conferred in sensitive H. aegyptius populations. A comparison of the frequency of this event induced by DNA of heterologous source (resistant Rd H. influenzae) and by DNA of homologous source (resistant H. aegyptius) supports the earlier report(3) which suggested a high degree of genetic homology between H. aegyptius and H. influenzae. The data suggest that a genetic factor (s) inherent in the receptor population influences the level of novobiocin resistance conferred by a given DNA. The genetic factors controlling streptomycin and novobiocin resistance have been demonstrated to be linked in H. aegyptius.</description><subject>DNA</subject><subject>DNA, Bacterial</subject><subject>Drug Resistance</subject><subject>Drug Resistance, Microbial</subject><subject>Genetics</subject><subject>Haemophilus</subject><subject>Haemophilus influenzae</subject><subject>Mutation</subject><subject>Novobiocin</subject><subject>Old Medline</subject><subject>Streptomycin</subject><issn>0037-9727</issn><issn>1535-3702</issn><issn>1535-3699</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1965</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kD1PwzAURS0EoqXwBxiQJ7a0dmzHyQilbZAqscCILMd5SVPlo9gJqPx6kraIjelJV-de6R2EbimZMhrSGSFMRtKXHqWh50cRE2doTAUTHgui6ByNB8AbiBG6cm5LCBXSDy7RiHI_4MIXY_S-7Gy7AYsXn0UKtQHcZFjjuMg3-AlyC4dgBTW0hcFxUzVlk-_xI7RfADWOp7ios7KD-lsD1nU6JBry_a4tOje9RheZLh3cnO4EvS0Xr_PYW7-snucPa88wTlvPhAETjBJDRKp9AZFJUhFwGqSZEZxliQwlDyEgMtGc-AljGclCIY1mkDAt2QTdH3d3tvnowLWqKpyBstQ1NJ1TISeUBzTsQf8IGts4ZyFTO1tU2u4VJWqQqn6lql6qOkjtS3en9S6pIP2rnCz2wOwIOJ2D2jadrftv_5v8Adx8flM</recordid><startdate>196503</startdate><enddate>196503</enddate><creator>Leidy, Grace</creator><creator>Jaffee, Iris</creator><creator>Alexander, Hattie E.</creator><general>SAGE Publications</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>196503</creationdate><title>Further Evidence of a High Degree of Genetic Homology Between H. influenzae and H. aegyptius.</title><author>Leidy, Grace ; Jaffee, Iris ; Alexander, Hattie E.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c341t-c8635310c05da25e9cbd56416dfc543fb78748e607ba402b33f0f857ca3eb3a73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1965</creationdate><topic>DNA</topic><topic>DNA, Bacterial</topic><topic>Drug Resistance</topic><topic>Drug Resistance, Microbial</topic><topic>Genetics</topic><topic>Haemophilus</topic><topic>Haemophilus influenzae</topic><topic>Mutation</topic><topic>Novobiocin</topic><topic>Old Medline</topic><topic>Streptomycin</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Leidy, Grace</creatorcontrib><creatorcontrib>Jaffee, Iris</creatorcontrib><creatorcontrib>Alexander, Hattie E.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Experimental biology and medicine (Maywood, N.J.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Leidy, Grace</au><au>Jaffee, Iris</au><au>Alexander, Hattie E.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Further Evidence of a High Degree of Genetic Homology Between H. influenzae and H. aegyptius.</atitle><jtitle>Experimental biology and medicine (Maywood, N.J.)</jtitle><addtitle>Proc Soc Exp Biol Med</addtitle><date>1965-03</date><risdate>1965</risdate><volume>118</volume><issue>3</issue><spage>671</spage><epage>679</epage><pages>671-679</pages><issn>0037-9727</issn><issn>1535-3702</issn><eissn>1535-3699</eissn><abstract>Summary
DNA-mediated transformation to novobiocin resistance has been conferred in sensitive H. aegyptius populations. A comparison of the frequency of this event induced by DNA of heterologous source (resistant Rd H. influenzae) and by DNA of homologous source (resistant H. aegyptius) supports the earlier report(3) which suggested a high degree of genetic homology between H. aegyptius and H. influenzae. The data suggest that a genetic factor (s) inherent in the receptor population influences the level of novobiocin resistance conferred by a given DNA. The genetic factors controlling streptomycin and novobiocin resistance have been demonstrated to be linked in H. aegyptius.</abstract><cop>London, England</cop><pub>SAGE Publications</pub><pmid>14264525</pmid><doi>10.3181/00379727-118-29935</doi><tpages>9</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0037-9727 |
| ispartof | Experimental biology and medicine (Maywood, N.J.), 1965-03, Vol.118 (3), p.671-679 |
| issn | 0037-9727 1535-3702 1535-3699 |
| language | eng |
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| source | MEDLINE; Alma/SFX Local Collection |
| subjects | DNA DNA, Bacterial Drug Resistance Drug Resistance, Microbial Genetics Haemophilus Haemophilus influenzae Mutation Novobiocin Old Medline Streptomycin |
| title | Further Evidence of a High Degree of Genetic Homology Between H. influenzae and H. aegyptius. |
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