Autosomally Determined Polymorphism of Glucose-6-Phosphate Dehydrogenase in Peromyscus

Glucose-6-phosphate dehydrogenase commonly occurs in at least two forms in most tissues of the deer mouse, Peromyscus maniculatus, as demonstrated by starch-gel electrophoresis. An autosomally determined genetic polymorphism in one of the enzymes was discovered. A hybrid molecule occurs in the heter...

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Veröffentlicht in:	Science (American Association for the Advancement of Science) 1965-05, Vol.148 (3673), p.1099-1100
Hauptverfasser:	Shaw, Charles R., Barto, Elizabeth
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal genetics Animals Chromosomes Dehydrogenases Electrophoresis Enzymes Gels Genetics Glucosephosphate Dehydrogenase Heterozygote Hybridity Hydrazines Liver - enzymology Mice Molecular genetics Old Medline Peromyscus Phenotypes Plants Polymorphism, Genetic Research Design Tissue Culture Techniques
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Beschreibung
Zusammenfassung:	Glucose-6-phosphate dehydrogenase commonly occurs in at least two forms in most tissues of the deer mouse, Peromyscus maniculatus, as demonstrated by starch-gel electrophoresis. An autosomally determined genetic polymorphism in one of the enzymes was discovered. A hybrid molecule occurs in the heterozygote; this suggests a dimeric structure of this enzyme.
ISSN:	0036-8075 1095-9203
DOI:	10.1126/science.148.3673.1099