Megakaryocytopoiesis in the Rat

Megakaryocytopoiesis in the Rat

MEGAKARYOCYTES have been thought by some to make up a self-maintaining compartment.1,2Observations of labeling with tritiated thymidine (H3TdR), however, have indicated that morphologically recognizable megakaryocytes are not self-perpetuating but are dependent on influx from precursor cells.3,4In t...

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Veröffentlicht in:Blood 1965-07, Vol.26 (1), p.20-35
Hauptverfasser: Ebbe, Shirley, Stohlman, Frederick
Format: Artikel
Sprache:eng
Schlagworte:
Blood Cell Count
Blood Platelets
Cell Division
DNA
Hematopoiesis
Megakaryocytes
Old Medline
Rats
Thrombopoiesis
Thymidine
Tritium
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Zusammenfassung:MEGAKARYOCYTES have been thought by some to make up a self-maintaining compartment.1,2Observations of labeling with tritiated thymidine (H3TdR), however, have indicated that morphologically recognizable megakaryocytes are not self-perpetuating but are dependent on influx from precursor cells.3,4In the present studies, megakaryocytopoiesis in the rat was further evaluated from the pattern of labeling with H3TdR.
ISSN:0006-4971
1528-0020
DOI:10.1182/blood.V26.1.20.20