Primary Bioassay of Human Tumor Stem Cells

Primary Bioassay of Human Tumor Stem Cells

A simple method has been developed to support human tumor stem cell colony growth in soft agar. The technique appears suitable for culture of a variety of neoplasms of differing histopathology. Tumor stem cell colonies arising from different types of cancer have differing growth characteristics and...

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Veröffentlicht in:Science (American Association for the Advancement of Science) 1977-07, Vol.197 (4302), p.461-463
Hauptverfasser: Hamburger, Anne W., Salmon, Sydney E.
Format: Artikel
Sprache:eng
Schlagworte:
Adenocarcinoma - pathology
Ascites
Bone marrow
Bone Marrow - pathology
Bone Marrow Cells
Cancer
Cell culture techniques
Cell growth
Cells, Cultured
Clone Cells
Culture Media
Female
Humans
Lymphoma - pathology
Multiple Myeloma - pathology
Neuroblastoma - pathology
Ovarian Neoplasms - pathology
Plasma cells
Polychlorinated biphenyls
Stem cells
Tumor stem cells
Tumors
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Beschreibung
Zusammenfassung:A simple method has been developed to support human tumor stem cell colony growth in soft agar. The technique appears suitable for culture of a variety of neoplasms of differing histopathology. Tumor stem cell colonies arising from different types of cancer have differing growth characteristics and colony morphology. This bioassay should be suitable for clinical studies of effects of anticancer drugs or irradiation on human tumor stem cells.
ISSN:0036-8075
1095-9203
DOI:10.1126/science.560061