Origin of Pulmonary Megakaryocytes

1. Evidence is presented which indicates that pulmonary megakaryocytes do not originate in the lungs but elsewhere in the body and are carried to the lungs in the venous blood. 2. Some megakaryocytes in the lungs evidently deliver platelets to the blood. 3. Surgery is a potent stimulus to megakaryoc...

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Veröffentlicht in:Blood 1965-05, Vol.25 (5), p.767-775
Hauptverfasser: Kaufman, Richard M., Airo, Romano, Pollack, Simeon, Crosby, William H., Doberneck, Raymond
Format: Artikel
Sprache:eng
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Zusammenfassung:1. Evidence is presented which indicates that pulmonary megakaryocytes do not originate in the lungs but elsewhere in the body and are carried to the lungs in the venous blood. 2. Some megakaryocytes in the lungs evidently deliver platelets to the blood. 3. Surgery is a potent stimulus to megakaryocyte production; the numbers of megakaryocytes found in the lung postoperatively is significantly increased.
ISSN:0006-4971
1528-0020
DOI:10.1182/blood.V25.5.767.767