Antibodies in Human Coccidioidomycosis: Immunoelectrophoretic Properties.

Summary An immunoelectrophoretic study was undertaken on two types of antibody detectable in human coccidioidomycosis, early precipitins and later complement-fixing antibodies. By using concentrated precipitin sera and dilute coccidioidal antigen, arcs of precipitation were produced which appeared t...

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Veröffentlicht in:Experimental biology and medicine (Maywood, N.J.) N.J.), 1965-01, Vol.118 (1), p.118-122
Hauptverfasser: Pappagianis, Demosthenes, Lindsey, Norma J., Smith, Charles E., Saito, Margaret T.
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Sprache:eng
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Zusammenfassung:Summary An immunoelectrophoretic study was undertaken on two types of antibody detectable in human coccidioidomycosis, early precipitins and later complement-fixing antibodies. By using concentrated precipitin sera and dilute coccidioidal antigen, arcs of precipitation were produced which appeared to correspond to the mobility of 19S β2 macro-globulin. Complement-fixing sera and cerebro-spinal fluids reacted with coccidioidal antigen to give precipitation arcs with the mobility of 7S γ2 globulin.
ISSN:0037-9727
1535-3702
1535-3699
DOI:10.3181/00379727-118-29773