The turnover of tritium from thymidine in tissues of the rat
The uptake and retention of tritium labelled thymidine has been studied in eight tissues of the normal rat, in most cases the turnover being followed up to 8 weeks after injection. The biological factors which contribute to the observed shape of thymidine turnover curves are discussed, in particular...
Gespeichert in:
| Veröffentlicht in: | Experimental cell research 1965, Vol.37 (1), p.117-131 |
|---|---|
| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 131 |
|---|---|
| container_issue | 1 |
| container_start_page | 117 |
| container_title | Experimental cell research |
| container_volume | 37 |
| creator | Steel, G.G. Lamerton, L.F. |
| description | The uptake and retention of tritium labelled thymidine has been studied in eight tissues of the normal rat, in most cases the turnover being followed up to 8 weeks after injection.
The biological factors which contribute to the observed shape of thymidine turnover curves are discussed, in particular the importance of the reutilisation of DNA tritium and radiation effects from the tritium label. |
| doi_str_mv | 10.1016/0014-4827(65)90162-X |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_83968569</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>001448276590162X</els_id><sourcerecordid>83968569</sourcerecordid><originalsourceid>FETCH-LOGICAL-c360t-721c7408d5a0dc74f3ea9dc4adc7d86ab8386df68e4cc661135a4babc0e33b1e3</originalsourceid><addsrcrecordid>eNp9kE1LAzEQhoMotlb_gcieRA-rySabZkEEKX5BwUuF3kI2maWR7qYm2UL_vekHevOUSXjemcyD0CXBdwQTfo8xYTkTxfiGl7dVeiny-REaElzhvGBFcYyGv8gAnYXwhTEWgvBTNCCs4JRiOkQPswVksfedW4PPXJNFb6Pt26zxrs3iYtNaYzvIbJdFG0IPYQelkFfxHJ00ahng4nCO0OfL82zylk8_Xt8nT9NcU45jPi6IHjMsTKmwSVVDQVVGM5UuRnBVCyq4abgApjXnhNBSsVrVGgOlNQE6Qtf7vivvvtMXomxt0LBcqg5cH6SgFRclrxLI9qD2LgQPjVx52yq_kQTLrTW5VSK3SiQv5c6anKfY1aF_X7dg_kIHTQl43AOQtlxb8DJoC50GYz3oKI2z_0_4AfmFfCE</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>83968569</pqid></control><display><type>article</type><title>The turnover of tritium from thymidine in tissues of the rat</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><creator>Steel, G.G. ; Lamerton, L.F.</creator><creatorcontrib>Steel, G.G. ; Lamerton, L.F.</creatorcontrib><description>The uptake and retention of tritium labelled thymidine has been studied in eight tissues of the normal rat, in most cases the turnover being followed up to 8 weeks after injection.
The biological factors which contribute to the observed shape of thymidine turnover curves are discussed, in particular the importance of the reutilisation of DNA tritium and radiation effects from the tritium label.</description><identifier>ISSN: 0014-4827</identifier><identifier>EISSN: 1090-2422</identifier><identifier>DOI: 10.1016/0014-4827(65)90162-X</identifier><identifier>PMID: 14263303</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Bone Marrow ; Colon ; DNA ; Humans ; Injections, Intraperitoneal ; Jejunum ; Lung ; Male ; Metabolism ; Old Medline ; Radiometry ; Rats ; Spleen ; Stomach ; Testis ; Thymidine ; Thymus Gland ; Tritium</subject><ispartof>Experimental cell research, 1965, Vol.37 (1), p.117-131</ispartof><rights>1965</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c360t-721c7408d5a0dc74f3ea9dc4adc7d86ab8386df68e4cc661135a4babc0e33b1e3</citedby><cites>FETCH-LOGICAL-c360t-721c7408d5a0dc74f3ea9dc4adc7d86ab8386df68e4cc661135a4babc0e33b1e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/001448276590162X$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3536,4009,27902,27903,27904,65309</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/14263303$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Steel, G.G.</creatorcontrib><creatorcontrib>Lamerton, L.F.</creatorcontrib><title>The turnover of tritium from thymidine in tissues of the rat</title><title>Experimental cell research</title><addtitle>Exp Cell Res</addtitle><description>The uptake and retention of tritium labelled thymidine has been studied in eight tissues of the normal rat, in most cases the turnover being followed up to 8 weeks after injection.
The biological factors which contribute to the observed shape of thymidine turnover curves are discussed, in particular the importance of the reutilisation of DNA tritium and radiation effects from the tritium label.</description><subject>Bone Marrow</subject><subject>Colon</subject><subject>DNA</subject><subject>Humans</subject><subject>Injections, Intraperitoneal</subject><subject>Jejunum</subject><subject>Lung</subject><subject>Male</subject><subject>Metabolism</subject><subject>Old Medline</subject><subject>Radiometry</subject><subject>Rats</subject><subject>Spleen</subject><subject>Stomach</subject><subject>Testis</subject><subject>Thymidine</subject><subject>Thymus Gland</subject><subject>Tritium</subject><issn>0014-4827</issn><issn>1090-2422</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1965</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1LAzEQhoMotlb_gcieRA-rySabZkEEKX5BwUuF3kI2maWR7qYm2UL_vekHevOUSXjemcyD0CXBdwQTfo8xYTkTxfiGl7dVeiny-REaElzhvGBFcYyGv8gAnYXwhTEWgvBTNCCs4JRiOkQPswVksfedW4PPXJNFb6Pt26zxrs3iYtNaYzvIbJdFG0IPYQelkFfxHJ00ahng4nCO0OfL82zylk8_Xt8nT9NcU45jPi6IHjMsTKmwSVVDQVVGM5UuRnBVCyq4abgApjXnhNBSsVrVGgOlNQE6Qtf7vivvvtMXomxt0LBcqg5cH6SgFRclrxLI9qD2LgQPjVx52yq_kQTLrTW5VSK3SiQv5c6anKfY1aF_X7dg_kIHTQl43AOQtlxb8DJoC50GYz3oKI2z_0_4AfmFfCE</recordid><startdate>1965</startdate><enddate>1965</enddate><creator>Steel, G.G.</creator><creator>Lamerton, L.F.</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>1965</creationdate><title>The turnover of tritium from thymidine in tissues of the rat</title><author>Steel, G.G. ; Lamerton, L.F.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c360t-721c7408d5a0dc74f3ea9dc4adc7d86ab8386df68e4cc661135a4babc0e33b1e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1965</creationdate><topic>Bone Marrow</topic><topic>Colon</topic><topic>DNA</topic><topic>Humans</topic><topic>Injections, Intraperitoneal</topic><topic>Jejunum</topic><topic>Lung</topic><topic>Male</topic><topic>Metabolism</topic><topic>Old Medline</topic><topic>Radiometry</topic><topic>Rats</topic><topic>Spleen</topic><topic>Stomach</topic><topic>Testis</topic><topic>Thymidine</topic><topic>Thymus Gland</topic><topic>Tritium</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Steel, G.G.</creatorcontrib><creatorcontrib>Lamerton, L.F.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Experimental cell research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Steel, G.G.</au><au>Lamerton, L.F.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The turnover of tritium from thymidine in tissues of the rat</atitle><jtitle>Experimental cell research</jtitle><addtitle>Exp Cell Res</addtitle><date>1965</date><risdate>1965</risdate><volume>37</volume><issue>1</issue><spage>117</spage><epage>131</epage><pages>117-131</pages><issn>0014-4827</issn><eissn>1090-2422</eissn><abstract>The uptake and retention of tritium labelled thymidine has been studied in eight tissues of the normal rat, in most cases the turnover being followed up to 8 weeks after injection.
The biological factors which contribute to the observed shape of thymidine turnover curves are discussed, in particular the importance of the reutilisation of DNA tritium and radiation effects from the tritium label.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>14263303</pmid><doi>10.1016/0014-4827(65)90162-X</doi><tpages>15</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0014-4827 |
| ispartof | Experimental cell research, 1965, Vol.37 (1), p.117-131 |
| issn | 0014-4827 1090-2422 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_83968569 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Bone Marrow Colon DNA Humans Injections, Intraperitoneal Jejunum Lung Male Metabolism Old Medline Radiometry Rats Spleen Stomach Testis Thymidine Thymus Gland Tritium |
| title | The turnover of tritium from thymidine in tissues of the rat |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-25T15%3A39%3A40IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=The%20turnover%20of%20tritium%20from%20thymidine%20in%20tissues%20of%20the%20rat&rft.jtitle=Experimental%20cell%20research&rft.au=Steel,%20G.G.&rft.date=1965&rft.volume=37&rft.issue=1&rft.spage=117&rft.epage=131&rft.pages=117-131&rft.issn=0014-4827&rft.eissn=1090-2422&rft_id=info:doi/10.1016/0014-4827(65)90162-X&rft_dat=%3Cproquest_cross%3E83968569%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=83968569&rft_id=info:pmid/14263303&rft_els_id=001448276590162X&rfr_iscdi=true |