The turnover of tritium from thymidine in tissues of the rat

The turnover of tritium from thymidine in tissues of the rat

The uptake and retention of tritium labelled thymidine has been studied in eight tissues of the normal rat, in most cases the turnover being followed up to 8 weeks after injection. The biological factors which contribute to the observed shape of thymidine turnover curves are discussed, in particular...

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Veröffentlicht in:Experimental cell research 1965, Vol.37 (1), p.117-131
Hauptverfasser: Steel, G.G., Lamerton, L.F.
Format: Artikel
Sprache:eng
Schlagworte:
Bone Marrow
Colon
DNA
Humans
Injections, Intraperitoneal
Jejunum
Lung
Male
Metabolism
Old Medline
Radiometry
Rats
Spleen
Stomach
Testis
Thymidine
Thymus Gland
Tritium
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Beschreibung
Zusammenfassung:The uptake and retention of tritium labelled thymidine has been studied in eight tissues of the normal rat, in most cases the turnover being followed up to 8 weeks after injection. The biological factors which contribute to the observed shape of thymidine turnover curves are discussed, in particular the importance of the reutilisation of DNA tritium and radiation effects from the tritium label.
ISSN:0014-4827
1090-2422
DOI:10.1016/0014-4827(65)90162-X