Absorption, Distribution and Excretion of Pentaerythritol and Pentaerythritol Tetranitrate by Mice

Absorption, Distribution and Excretion of Pentaerythritol and Pentaerythritol Tetranitrate by Mice

Summary Radioactive PE and PETN were administered orally to mice and their fate was followed by scintillation spectrome-try, thin layer chromatography and radio-scanning. PE was absorbed rapidly and excreted unchanged whereas PETN was absorbed slowly and excreted as PE.

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Bibliographische Detailangaben
Veröffentlicht in:Experimental biology and medicine (Maywood, N.J.) N.J.), 1965-02, Vol.118 (2), p.311-315
Hauptverfasser: DiCarlo, Frederick J., Hartigan, James M., Coutinho, Claude B., Phillips, George E.
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Body Fluids
Carbon Isotopes
Chromatography
Glycols
Metabolism
Mice
Old Medline
Pentaerythritol Tetranitrate
Propylene Glycols
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Beschreibung
Zusammenfassung:Summary Radioactive PE and PETN were administered orally to mice and their fate was followed by scintillation spectrome-try, thin layer chromatography and radio-scanning. PE was absorbed rapidly and excreted unchanged whereas PETN was absorbed slowly and excreted as PE.
ISSN:0037-9727
1535-3702
1535-3699
DOI:10.3181/00379727-118-29829