Isolation of 2,3;22,23-dioxidosqualene and 24,25-oxidolanosterol from yeast

The compound 2,3;22,23-dioxidosqualene has been found to accumulate in yeast grown in the presence of 10 −4 m 3β-(β-dimethylaminoethoxy)-androst-5-en-17-one. Subsequent removal of the latter compound permits the formation of 24,25-oxidolanosterol and more polar unidentified compounds.

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Bibliographische Detailangaben
Veröffentlicht in:	Archives of biochemistry and biophysics 1977-04, Vol.180 (2), p.465-471
Hauptverfasser:	Field, Ruth B., Holmlund, Chester E.
Format:	Artikel
Sprache:	eng
Schlagworte:	17-Ketosteroids - metabolism Androstenes - metabolism Ethers, Cyclic - isolation & purification Lanosterol - analogs & derivatives Lanosterol - isolation & purification Saccharomyces cerevisiae - analysis Squalene - analogs & derivatives Squalene - isolation & purification
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Beschreibung
Zusammenfassung:	The compound 2,3;22,23-dioxidosqualene has been found to accumulate in yeast grown in the presence of 10 −4 m 3β-(β-dimethylaminoethoxy)-androst-5-en-17-one. Subsequent removal of the latter compound permits the formation of 24,25-oxidolanosterol and more polar unidentified compounds.
ISSN:	0003-9861 1096-0384
DOI:	10.1016/0003-9861(77)90061-3