Recognition of Mismatched Base Pairs in DNA
Mismatch binding ligand (MBL) selectively binds to mismatched base pairs with discrimination of the nucleotide bases composing the mismatch. This review focuses on the inside story regarding the molecular design of MBL and its function, and potential application in genomic science.
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Veröffentlicht in: | Bulletin of the Chemical Society of Japan 2009-09, Vol.82 (9), p.1055-1069 |
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Format: | Artikel |
Sprache: | eng |
Online-Zugang: | Volltext |
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Zusammenfassung: | Mismatch binding ligand (MBL) selectively binds to mismatched base pairs with discrimination of the nucleotide bases composing the mismatch. This review focuses on the inside story regarding the molecular design of MBL and its function, and potential application in genomic science. |
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ISSN: | 0009-2673 1348-0634 1348-0634 |
DOI: | 10.1246/bcsj.82.1055 |