Presence of ribonucleotide sequences complementary to rous sarcoma virus (RSV) RNA in chicken cells infected with RSV

Presence of ribonucleotide sequences complementary to rous sarcoma virus (RSV) RNA in chicken cells infected with RSV

RNA-RNA molecular hybridization between [ 125I]RNA from Rous sarcoma virus virions and RNAs isolated from various subcellular fractions, i.e. nuclei, mitochondria, free and membrane-bound polyribosomes, from tumors induced by RSV in chickens resulted in the formation of RNAase-resistant hybrids only...

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Veröffentlicht in:Cancer letters 1977-05, Vol.2 (6), p.349-354
Hauptverfasser: Shaposhnikov, Jacob D., Ratovitski, Edward A., Kuznetsov, Oleg K.
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Avian Sarcoma Viruses - metabolism
Base Sequence
Chickens
Mitochondria - metabolism
Nucleic Acid Hybridization
Polyribosomes - metabolism
RNA, Neoplasm - metabolism
RNA, Viral - metabolism
Sarcoma, Avian - metabolism
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Zusammenfassung:RNA-RNA molecular hybridization between [ 125I]RNA from Rous sarcoma virus virions and RNAs isolated from various subcellular fractions, i.e. nuclei, mitochondria, free and membrane-bound polyribosomes, from tumors induced by RSV in chickens resulted in the formation of RNAase-resistant hybrids only with the RNA of mitochondria and membrane-bound polysomes. The origin of complementary regions in the RNAs from these organelles is discussed.
ISSN:0304-3835
1872-7980
DOI:10.1016/S0304-3835(77)80016-5