ADH and ALDH genotype profiles in Caucasians with alcohol-related problems and controls

ADH and ALDH genotype profiles in Caucasians with alcohol-related problems and controls

Eighty‐two Caucasian patients receiving treatment for alcohol‐related problems and eighty four controls were DNA typed for variants in the alcohol dehydrogenase (ADH2 and ADH3) and mitochondrial aldehyde dehydrogenase (ALDHJ gene loci. No association was observed between individual, or combined gene...

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Veröffentlicht in:Addiction (Abingdon, England) England), 1993-03, Vol.88 (3), p.383-388
Hauptverfasser: GILDER, FAY J., HODGKINSON, STEVE, MURRAY, ROBIN M.
Format: Artikel
Sprache:eng
Schlagworte:
Addictive behaviors
Adult
Adult and adolescent clinical studies
Alcohol Dehydrogenase - genetics
Alcohol related disorders
Alcoholism
Alcoholism - genetics
Aldehyde Dehydrogenase - genetics
Biological and medical sciences
Female
Gene Frequency
Genetic aspects
Genetics
Genotype
Humans
Isoenzymes - genetics
Male
Medical sciences
Middle Aged
Polymerase Chain Reaction
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
Risk Factors
Substance abuse
United Kingdom
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Zusammenfassung:Eighty‐two Caucasian patients receiving treatment for alcohol‐related problems and eighty four controls were DNA typed for variants in the alcohol dehydrogenase (ADH2 and ADH3) and mitochondrial aldehyde dehydrogenase (ALDHJ gene loci. No association was observed between individual, or combined gene frequencies and the presence of alcohol‐related problems.
ISSN:0965-2140
1360-0443
DOI:10.1111/j.1360-0443.1993.tb00825.x