Formation of Complexes between Basic Proteins of Leucocytes and Plasma Globulins

RECENT studies have shown that cationic proteins from leucocytes produce tissue injury and responses characteristic of immunological reactions 1–4 . In an earlier publication we put forward the hypothesis that homograft rejection may be caused by such cationic proteins 5 . The specificity of the homograft reaction could only occur if the basic protein were transported to the homograft site via specific antibody (globulin) or in cells which had specificity through some chemotactic response of the cell to antigen.