Pancreatic alpha and beta cell functions in cystic fibrosis

Pancreatic alpha and beta cell functions in cystic fibrosis

Insulin and glucagon secretions were studied during oral glucose tolerance testing and arginine infusion in 13 patients with cystic fibrosis. Two groups of patients were identified; Group I (N=6) whose OGTT was entirely normal and Group II (N=7) who had some abnormality in glucose during OGTT. In ea...

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Veröffentlicht in:The Journal of pediatrics 1977-05, Vol.90 (5), p.751-755
Hauptverfasser: Lippe, Barbara M., Sperling, Mark A., Dooley, Richard R.
Format: Artikel
Sprache:eng
Schlagworte:
Adolescent
Adult
Arginine
Child
Cystic Fibrosis - complications
Cystic Fibrosis - physiopathology
Female
Glucagon - metabolism
Glucose Tolerance Test
Humans
Insulin - metabolism
Insulin Secretion
Islets of Langerhans - physiopathology
Male
Prediabetic State - complications
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Zusammenfassung:Insulin and glucagon secretions were studied during oral glucose tolerance testing and arginine infusion in 13 patients with cystic fibrosis. Two groups of patients were identified; Group I (N=6) whose OGTT was entirely normal and Group II (N=7) who had some abnormality in glucose during OGTT. In each group basal glucagon concentrations were normal and supressed appropriately (p
ISSN:0022-3476
1097-6833
DOI:10.1016/S0022-3476(77)81241-9