Preparation of estrone and estradiol antigens through carbon 15 of these estrogens

Preparation of estrone and estradiol antigens through carbon 15 of these estrogens

Estrone (E 1) and estradiol (E 2) 15ξ-carboxymethyl derivatives were prepared and coupled to bovine serum albumin. Studies of the immunsera induced by these antigens showed that they have high affinity and specificity.

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Bibliographische Detailangaben
Veröffentlicht in:Steroids 1977-02, Vol.29 (2), p.161-170
Hauptverfasser: Linder, Monique, Desfosses, Bernard, Emiliozzi, Roméo
Format: Artikel
Sprache:eng
Schlagworte:
Antigens
Cross Reactions
Estradiol - immunology
Estrone - immunology
Radioimmunoassay - methods
Serum Albumin, Bovine
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Beschreibung
Zusammenfassung:Estrone (E 1) and estradiol (E 2) 15ξ-carboxymethyl derivatives were prepared and coupled to bovine serum albumin. Studies of the immunsera induced by these antigens showed that they have high affinity and specificity.
ISSN:0039-128X
1878-5867
DOI:10.1016/0039-128X(77)90036-8