In Vitro Metabolism of 4-Androstene-3,17-Dione by Human Submaxillary Gland Homogenates

Tritiated 4-androstene-3,17-dione was incubated with human submaxillary gland homoaenates. In 180-minute incubations, human submaxillary gland converted 4-androstene-3, 17-dione predominately to testosterone and to a lesser extent, 5α-androstane-3α,17β-diol and androsterone.

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Veröffentlicht in:	Journal of dental research 1977-03, Vol.56 (3), p.332-334
Hauptverfasser:	Coffey, James C., Crutchfield, William C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Androstenediols - biosynthesis Androstenedione - metabolism Culture Techniques Dentistry Female Humans Male Middle Aged Submandibular Gland - metabolism Testosterone - biosynthesis
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container_title	Journal of dental research
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description	Tritiated 4-androstene-3,17-dione was incubated with human submaxillary gland homoaenates. In 180-minute incubations, human submaxillary gland converted 4-androstene-3, 17-dione predominately to testosterone and to a lesser extent, 5α-androstane-3α,17β-diol and androsterone.
doi_str_mv	10.1177/00220345770560032101
format	Article
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subjects	Adult Aged Androstenediols - biosynthesis Androstenedione - metabolism Culture Techniques Dentistry Female Humans Male Middle Aged Submandibular Gland - metabolism Testosterone - biosynthesis
title	In Vitro Metabolism of 4-Androstene-3,17-Dione by Human Submaxillary Gland Homogenates
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