In Vitro Metabolism of 4-Androstene-3,17-Dione by Human Submaxillary Gland Homogenates

In Vitro Metabolism of 4-Androstene-3,17-Dione by Human Submaxillary Gland Homogenates

Tritiated 4-androstene-3,17-dione was incubated with human submaxillary gland homoaenates. In 180-minute incubations, human submaxillary gland converted 4-androstene-3, 17-dione predominately to testosterone and to a lesser extent, 5α-androstane-3α,17β-diol and androsterone.

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Bibliographische Detailangaben
Veröffentlicht in:Journal of dental research 1977-03, Vol.56 (3), p.332-334
Hauptverfasser: Coffey, James C., Crutchfield, William C.
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Aged
Androstenediols - biosynthesis
Androstenedione - metabolism
Culture Techniques
Dentistry
Female
Humans
Male
Middle Aged
Submandibular Gland - metabolism
Testosterone - biosynthesis
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Zusammenfassung:Tritiated 4-androstene-3,17-dione was incubated with human submaxillary gland homoaenates. In 180-minute incubations, human submaxillary gland converted 4-androstene-3, 17-dione predominately to testosterone and to a lesser extent, 5α-androstane-3α,17β-diol and androsterone.
ISSN:0022-0345
1544-0591
DOI:10.1177/00220345770560032101