Pathogenicity of the intercellular antibodies of pemphigus and their periodic removal from the circulation by plasmapheresis

Pathogenicity of the intercellular antibodies of pemphigus and their periodic removal from the circulation by plasmapheresis

SUMMARY The authors are convinced that the intercellular antibodies of pemphigus are pathogenic. Consequently periodic plasmapheresis in two patients with pemphigus has been performed to remove the antibodies from the circulation. After larger plasma‐exchanges there was a decrease of the antibody ti...

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Veröffentlicht in:British journal of dermatology (1951) 1978-02, Vol.98 (2), p.237-241
Hauptverfasser: RUOCCO, V., ROSSI, A., ARGENZIANO, G., ASTARITA, C., ALVIGGI, L., FARZATI, B., PAPALEO, G.
Format: Artikel
Sprache:eng
Schlagworte:
Autoantibodies - analysis
Humans
Pemphigus - immunology
Pemphigus - therapy
Plasmapheresis
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Zusammenfassung:SUMMARY The authors are convinced that the intercellular antibodies of pemphigus are pathogenic. Consequently periodic plasmapheresis in two patients with pemphigus has been performed to remove the antibodies from the circulation. After larger plasma‐exchanges there was a decrease of the antibody titre and a parallel improvement of the clinical condition.
ISSN:0007-0963
1365-2133
DOI:10.1111/j.1365-2133.1978.tb01630.x