DNA synthesis in rat sarcoma and liver: The effect of starvation

DNA synthesis in rat sarcoma and liver: The effect of starvation

Starvation in tumor-bearing rats results in augmentation of DNA synthesis as measured by tritiated thymidine incorporation into tumor DNA as compared to normally fed tumor-bearing control animals. Liver DNA synthesis fell to 20% of control with starvation. Acute fasting may result in increased tumor...

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Veröffentlicht in:The Journal of surgical research 1977-03, Vol.22 (3), p.281-286
Hauptverfasser: Reilly, James J., Thomas Goodgame, J., Jones, Daniel C., Brennan, Murray F.
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Body Water - metabolism
Body Weight
DNA - biosynthesis
DNA, Neoplasm - biosynthesis
Liver - metabolism
Male
Rats
Sarcoma, Experimental - metabolism
Starvation - metabolism
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Zusammenfassung:Starvation in tumor-bearing rats results in augmentation of DNA synthesis as measured by tritiated thymidine incorporation into tumor DNA as compared to normally fed tumor-bearing control animals. Liver DNA synthesis fell to 20% of control with starvation. Acute fasting may result in increased tumor growth as reflected by this index.
ISSN:0022-4804
1095-8673
DOI:10.1016/0022-4804(77)90144-5