Prinzmetal's variant angina--response to verapamil

A patient with frequent attacks of Prinzmetal's variant angina complicated by ventricular tachycardia and ventricular fibrillation is described in whom these episodes persisted daily during 4 weeks of hospital observation in spite of treatment with nitrates, alpha-adrenergic-blocking drugs, and anticholinergic agents. The oral administration of verapamil, an investigational vasodilator drug, led to prompt and complete resolution of the attacks.