Studies on the rosette inhibition assay. Results using monkey lymphocytes

Studies on the rosette inhibition assay. Results using monkey lymphocytes

Results obtained using a modified rosette inhibition assay with human and monkey lymphocytes were compared. The monkey lymphocytes tended to yield lower titers against a series of antithymocyte globulin preparations. Titers or relative rosette inhibition activities obtained with monkey lymphocytes c...

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Veröffentlicht in:Transplantation 1977-02, Vol.23 (2), p.124-127
1. Verfasser: Parcells, A J
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Antilymphocyte Serum - pharmacology
Haplorhini
Humans
Immunologic Techniques
Lymphocytes - immunology
Macaca mulatta
Skin Transplantation
T-Lymphocytes - immunology
Transplantation, Homologous
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Zusammenfassung:Results obtained using a modified rosette inhibition assay with human and monkey lymphocytes were compared. The monkey lymphocytes tended to yield lower titers against a series of antithymocyte globulin preparations. Titers or relative rosette inhibition activities obtained with monkey lymphocytes correlated more poorly with skin graft prolongation in monkeys than assays using human lymphocytes in previous studies.
ISSN:0041-1337
DOI:10.1097/00007890-197702000-00003