Application of a Convective Diffusion Model to Membrane Transport
Studies were carried out on the permeation rate of butamben through a dimethicone membrane. Under conditions of “aqueous diffusion layer control,” the permeation rate was accurately described by a mathematical model based on convective diffusion theory. In accordance with the model, the rate of perm...
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| Veröffentlicht in: | Journal of pharmaceutical sciences 1977-01, Vol.66 (1), p.137-139 |
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| container_end_page | 139 |
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| container_title | Journal of pharmaceutical sciences |
| container_volume | 66 |
| creator | Nelson, K.G. Shah, A.C. |
| description | Studies were carried out on the permeation rate of butamben through a dimethicone membrane. Under conditions of “aqueous diffusion layer control,” the permeation rate was accurately described by a mathematical model based on convective diffusion theory. In accordance with the model, the rate of permeation from a saturated donor phase was shown to be equal to the rate of dissolution from a pure solid. |
| doi_str_mv | 10.1002/jps.2600660141 |
| format | Article |
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Under conditions of “aqueous diffusion layer control,” the permeation rate was accurately described by a mathematical model based on convective diffusion theory. In accordance with the model, the rate of permeation from a saturated donor phase was shown to be equal to the rate of dissolution from a pure solid.</description><identifier>ISSN: 0022-3549</identifier><identifier>EISSN: 1520-6017</identifier><identifier>DOI: 10.1002/jps.2600660141</identifier><identifier>PMID: 833731</identifier><language>eng</language><publisher>Washington: Elsevier Inc</publisher><subject>Aminobenzoates - metabolism ; Biological Transport ; Butamben-permeation rate through dimethicone membrane ; Butamben—permeation rate through dimethicone membrane, convective diffusion model ; convective diffusion model ; convective-model applied to permeation rate of butamben through dimethicone membrane ; Diffusion ; Diffusion, convective—model applied to permeation rate of butamben through dimethicone membrane ; Membrane transport convective diffusion model applied to permeation rate of butamben through dimethicone membrane ; Membranes - metabolism ; Models, Biological ; Permeability ; Permeation rate-butamben through dimethicone membrane ; Permeation rate—butamben through dimethicone membrane, convective diffusion model ; Rheology ; Space life sciences</subject><ispartof>Journal of pharmaceutical sciences, 1977-01, Vol.66 (1), p.137-139</ispartof><rights>1977 Wiley-Liss, Inc., A Wiley Company</rights><rights>Copyright © 1977 Wiley‐Liss, Inc., A Wiley Company</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4261-6756439c22d9da03978a1330ca754457e281a46ac80ddac1ca7470038f71b8dd3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fjps.2600660141$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fjps.2600660141$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/833731$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Nelson, K.G.</creatorcontrib><creatorcontrib>Shah, A.C.</creatorcontrib><title>Application of a Convective Diffusion Model to Membrane Transport</title><title>Journal of pharmaceutical sciences</title><addtitle>J. Pharm. Sci</addtitle><description>Studies were carried out on the permeation rate of butamben through a dimethicone membrane. Under conditions of “aqueous diffusion layer control,” the permeation rate was accurately described by a mathematical model based on convective diffusion theory. In accordance with the model, the rate of permeation from a saturated donor phase was shown to be equal to the rate of dissolution from a pure solid.</description><subject>Aminobenzoates - metabolism</subject><subject>Biological Transport</subject><subject>Butamben-permeation rate through dimethicone membrane</subject><subject>Butamben—permeation rate through dimethicone membrane, convective diffusion model</subject><subject>convective diffusion model</subject><subject>convective-model applied to permeation rate of butamben through dimethicone membrane</subject><subject>Diffusion</subject><subject>Diffusion, convective—model applied to permeation rate of butamben through dimethicone membrane</subject><subject>Membrane transport convective diffusion model applied to permeation rate of butamben through dimethicone membrane</subject><subject>Membranes - metabolism</subject><subject>Models, Biological</subject><subject>Permeability</subject><subject>Permeation rate-butamben through dimethicone membrane</subject><subject>Permeation rate—butamben through dimethicone membrane, convective diffusion model</subject><subject>Rheology</subject><subject>Space life sciences</subject><issn>0022-3549</issn><issn>1520-6017</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1977</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkUtPAyEUhYnxVR9bVy5m5W4qDDPALJtqWx9VE2tcEgp3EnRaRphW_fdixmhcGDcQON854R4QOiK4TzDOTp-a0M8YxoxhkpMN1CNFhtN44JuoF4EspUVe7qK9EJ5wxHBR7KBtQSmnpIcGg6aprVatdcvEVYlKhm65Bt3aNSRntqpW4VOZOgN10rpkCou5V0tIZnENjfPtAdqqVB3g8GvfRw-j89lwkl7fji-Gg-tU5xkjKeMFy2mps8yURmFacqEIpVgrXuR5wSETROVMaYGNUZrE-5xjTEXFyVwYQ_fRSZfbePeygtDKhQ0a6jq-xq2CFFTE-SmLYL8DtXcheKhk4-1C-XdJsPysTMbK5E9l0XD8lbyaL8B8411HUS47-dXW8P5PmLy8u_8VnXZeG1p4-_Yq_ywZp7yQjzdjOZvcs8fZaCyvIi86HmKTawteBm1hqcFYHz9FGmf_muIDv3mYKA</recordid><startdate>197701</startdate><enddate>197701</enddate><creator>Nelson, K.G.</creator><creator>Shah, A.C.</creator><general>Elsevier Inc</general><general>Wiley Subscription Services, Inc., A Wiley Company</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>197701</creationdate><title>Application of a Convective Diffusion Model to Membrane Transport</title><author>Nelson, K.G. ; Shah, A.C.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4261-6756439c22d9da03978a1330ca754457e281a46ac80ddac1ca7470038f71b8dd3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1977</creationdate><topic>Aminobenzoates - metabolism</topic><topic>Biological Transport</topic><topic>Butamben-permeation rate through dimethicone membrane</topic><topic>Butamben—permeation rate through dimethicone membrane, convective diffusion model</topic><topic>convective diffusion model</topic><topic>convective-model applied to permeation rate of butamben through dimethicone membrane</topic><topic>Diffusion</topic><topic>Diffusion, convective—model applied to permeation rate of butamben through dimethicone membrane</topic><topic>Membrane transport convective diffusion model applied to permeation rate of butamben through dimethicone membrane</topic><topic>Membranes - metabolism</topic><topic>Models, Biological</topic><topic>Permeability</topic><topic>Permeation rate-butamben through dimethicone membrane</topic><topic>Permeation rate—butamben through dimethicone membrane, convective diffusion model</topic><topic>Rheology</topic><topic>Space life sciences</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Nelson, K.G.</creatorcontrib><creatorcontrib>Shah, A.C.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of pharmaceutical sciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Nelson, K.G.</au><au>Shah, A.C.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Application of a Convective Diffusion Model to Membrane Transport</atitle><jtitle>Journal of pharmaceutical sciences</jtitle><addtitle>J. Pharm. Sci</addtitle><date>1977-01</date><risdate>1977</risdate><volume>66</volume><issue>1</issue><spage>137</spage><epage>139</epage><pages>137-139</pages><issn>0022-3549</issn><eissn>1520-6017</eissn><abstract>Studies were carried out on the permeation rate of butamben through a dimethicone membrane. Under conditions of “aqueous diffusion layer control,” the permeation rate was accurately described by a mathematical model based on convective diffusion theory. In accordance with the model, the rate of permeation from a saturated donor phase was shown to be equal to the rate of dissolution from a pure solid.</abstract><cop>Washington</cop><pub>Elsevier Inc</pub><pmid>833731</pmid><doi>10.1002/jps.2600660141</doi><tpages>3</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0022-3549 |
| ispartof | Journal of pharmaceutical sciences, 1977-01, Vol.66 (1), p.137-139 |
| issn | 0022-3549 1520-6017 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_83814136 |
| source | MEDLINE; Wiley Online Library Journals Frontfile Complete; Alma/SFX Local Collection |
| subjects | Aminobenzoates - metabolism Biological Transport Butamben-permeation rate through dimethicone membrane Butamben—permeation rate through dimethicone membrane, convective diffusion model convective diffusion model convective-model applied to permeation rate of butamben through dimethicone membrane Diffusion Diffusion, convective—model applied to permeation rate of butamben through dimethicone membrane Membrane transport convective diffusion model applied to permeation rate of butamben through dimethicone membrane Membranes - metabolism Models, Biological Permeability Permeation rate-butamben through dimethicone membrane Permeation rate—butamben through dimethicone membrane, convective diffusion model Rheology Space life sciences |
| title | Application of a Convective Diffusion Model to Membrane Transport |
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