Sister Mary Joseph’s nodule derived from pancreatic cancer

Background/Purpose Umbilical metastases known as Sister Mary Joseph’s nodules (SMJNs) occur rarely. They are an uncommon clinical or radiographic finding, and are rare as the first sign of a malignant disease. Pancreatic cancer presenting as an SMJN is a rare phenomenon, and is the source of an SMJN in 9% of cases. Case presentation We experienced four cases of SMJN derived from pancreatic cancer. All cases originated in the tail and/or body of the pancreas. Discussion Herein, we introduce a case with pathognomonic imaging findings. We also present the results of our review of recently published papers about SMJN, done by conducting a PubMed search.