The Effect of Endotoxin on Skin Homografts in Rabbits

Administration of endotoxin to rabbits results in the accelerated rejection of first-set skin homografts. The production of endotoxin tolerance suspends this effect of endotoxin on first-set skin homografts. This action of endotoxin is limited to homografts and does not affect autografts.

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Veröffentlicht in:The Journal of immunology (1950) 1964-11, Vol.93 (5), p.742-748
Hauptverfasser: Al-Askari, Salah, Zweiman, B, Lawrence, H. S, Thomas, L
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Sprache:eng
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Zusammenfassung:Administration of endotoxin to rabbits results in the accelerated rejection of first-set skin homografts. The production of endotoxin tolerance suspends this effect of endotoxin on first-set skin homografts. This action of endotoxin is limited to homografts and does not affect autografts.
ISSN:0022-1767
1550-6606
DOI:10.4049/jimmunol.93.5.742