Physiologically Active Substances from Marine Sponges V: Isolation of Physiologically Active Compounds from the Sponge Verongia archeri

Methanolic extracts of hard and soft varieties of the sponge Verongia archeri were found to contain similar compounds. An isolation procedure and the structures of 2-(3′,5′-dibromo-4′-hydroxyphenyl)-acetamide, 1-(3′,5′-dibromo-1′,6′-dihydroxy-4′-methoxycyclohexa- 2′,4′-diene)acetonitrile,and 2-oxo-5,7-dibromo-6-methoxy-9-hydroxy- 8,9-dihydrocoumarin from one variety are described.