Physicochemical Studies on Water contained in Solid Medicaments. II: Temperature Dependence of Dielectric Properties and Pyrolysis of Hydrated Crystals

Apparent dielectric constant and dielectric loss of hydrates in accordance with temperature changes were measured and by comparison of these values with weight changes as measured by thermobalance, nature of water in hydrates was examined in detail. This method was found to make simple discrimination of water of crystallization, sorbed water, and free water. The method also enables measurement of melting and decomposition points.