Effect of phosvitin on smooth muscle “in vitro”
Phosvitin's activity on isolated guinea-pig ileum and on normal and hypoxic rat aortic strips was studied. Under both experimental conditions, phosvitin enhanced the responses of aortic strips to norepinephrine, whereas the phosphorylated comparison compounds, phosphocreatine, phosphoserine and...
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| Veröffentlicht in: | Pharmacological research communications 1976-06, Vol.8 (3), p.319-323 |
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| creator | Caprino, L. Borrelli, F. Falchetti, R. Politi, L. |
| description | Phosvitin's activity on isolated guinea-pig ileum and on normal and hypoxic rat aortic strips was studied. Under both experimental conditions, phosvitin enhanced the responses of aortic strips to norepinephrine, whereas the phosphorylated comparison compounds, phosphocreatine, phosphoserine and KH
2PO
4, were without effect.
In the isolated guinea-pig ileum test, phosvitin showed no spasmogenic or spasmolytic activity. |
| doi_str_mv | 10.1016/0031-6989(76)90021-7 |
| format | Article |
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2PO
4, were without effect.
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2PO
4, were without effect.
In the isolated guinea-pig ileum test, phosvitin showed no spasmogenic or spasmolytic activity.</description><subject>Animals</subject><subject>Aorta - drug effects</subject><subject>Egg Proteins - pharmacology</subject><subject>Guinea Pigs</subject><subject>Ileum - drug effects</subject><subject>In Vitro Techniques</subject><subject>Male</subject><subject>Muscle, Smooth - drug effects</subject><subject>Norepinephrine - antagonists & inhibitors</subject><subject>Phosphates - pharmacology</subject><subject>Phosphocreatine - pharmacology</subject><subject>Phosphorus - pharmacology</subject><subject>Phosvitin - pharmacology</subject><subject>Potassium - pharmacology</subject><subject>Rats</subject><subject>Serine - pharmacology</subject><issn>0031-6989</issn><issn>1879-2936</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1976</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kMtKAzEUhoMotVbfQGFWoovRk6TNZSNIqRcouNF1mMkkNDLT1GSm4K4Poi_XJzG9IK5cHc75__8czofQOYYbDJjdAlCcMynkFWfXEoDgnB-gPhZc5kRSdoj6v5ZjdBLje2oJw9BDPQyESQZ9RCfWGt1m3maLmY9L17p55udZbLxvZ1nTRV2bbL36SuMkBr9efZ-iI1vU0Zzt6wC9PUxex0_59OXxeXw_zTUhuM1HphSSgq3IyAgqMNMCOBDLoOQGOCk5oUNpqMTUimJosSYjCUxypklpcUUH6HK3dxH8R2diqxoXtanrYm58F5WgTAhCWTIOd0YdfIzBWLUIrinCp8KgNqzUBoTagFCcqS0rxVPsYr-_KxtT_Qlt4ST9bqeb9OTSmaCidmauTeVCYqYq7_4_8ANr1ngO</recordid><startdate>197606</startdate><enddate>197606</enddate><creator>Caprino, L.</creator><creator>Borrelli, F.</creator><creator>Falchetti, R.</creator><creator>Politi, L.</creator><general>Elsevier B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>197606</creationdate><title>Effect of phosvitin on smooth muscle “in vitro”</title><author>Caprino, L. ; Borrelli, F. ; Falchetti, R. ; Politi, L.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c221t-5eb8930fd25e83816c80702f60b7e072b72349e3913f8a4f1c25906976c2bf1d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1976</creationdate><topic>Animals</topic><topic>Aorta - drug effects</topic><topic>Egg Proteins - pharmacology</topic><topic>Guinea Pigs</topic><topic>Ileum - drug effects</topic><topic>In Vitro Techniques</topic><topic>Male</topic><topic>Muscle, Smooth - drug effects</topic><topic>Norepinephrine - antagonists & inhibitors</topic><topic>Phosphates - pharmacology</topic><topic>Phosphocreatine - pharmacology</topic><topic>Phosphorus - pharmacology</topic><topic>Phosvitin - pharmacology</topic><topic>Potassium - pharmacology</topic><topic>Rats</topic><topic>Serine - pharmacology</topic><toplevel>online_resources</toplevel><creatorcontrib>Caprino, L.</creatorcontrib><creatorcontrib>Borrelli, F.</creatorcontrib><creatorcontrib>Falchetti, R.</creatorcontrib><creatorcontrib>Politi, L.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Pharmacological research communications</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Caprino, L.</au><au>Borrelli, F.</au><au>Falchetti, R.</au><au>Politi, L.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effect of phosvitin on smooth muscle “in vitro”</atitle><jtitle>Pharmacological research communications</jtitle><addtitle>Pharmacol Res Commun</addtitle><date>1976-06</date><risdate>1976</risdate><volume>8</volume><issue>3</issue><spage>319</spage><epage>323</epage><pages>319-323</pages><issn>0031-6989</issn><eissn>1879-2936</eissn><abstract>Phosvitin's activity on isolated guinea-pig ileum and on normal and hypoxic rat aortic strips was studied. Under both experimental conditions, phosvitin enhanced the responses of aortic strips to norepinephrine, whereas the phosphorylated comparison compounds, phosphocreatine, phosphoserine and KH
2PO
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| fulltext | fulltext |
| identifier | ISSN: 0031-6989 |
| ispartof | Pharmacological research communications, 1976-06, Vol.8 (3), p.319-323 |
| issn | 0031-6989 1879-2936 |
| language | eng |
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| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Animals Aorta - drug effects Egg Proteins - pharmacology Guinea Pigs Ileum - drug effects In Vitro Techniques Male Muscle, Smooth - drug effects Norepinephrine - antagonists & inhibitors Phosphates - pharmacology Phosphocreatine - pharmacology Phosphorus - pharmacology Phosvitin - pharmacology Potassium - pharmacology Rats Serine - pharmacology |
| title | Effect of phosvitin on smooth muscle “in vitro” |
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