Hepatitis B surface antigenaemia in Kenyans with chronic liver disease
Fifty Kenyan patients with chronic liver disease or hepatocellular carcinoma were tested for hepatitis B surface antigenaemia by radioimmunoassay. The hepatitis B surface antigen was detected in 77% of the patients with chronic persistent or chronic aggressive hepatitis, or cirrhosis confirmed by li...
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Veröffentlicht in: | Transactions of the Royal Society of Tropical Medicine and Hygiene 1976, Vol.70 (5), p.462-465 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Fifty Kenyan patients with chronic liver disease or hepatocellular carcinoma were tested for hepatitis B surface antigenaemia by radioimmunoassay. The hepatitis B surface antigen was detected in 77% of the patients with chronic persistent or chronic aggressive hepatitis, or cirrhosis confirmed by liver biopsy, compared with 15% in a control group. All six patients with hepatocellular carcinoma had detectable hepatitis B surface antigen or antibody. 50% of the controls had hepatitis B surface antibody in their plasma detectable by haemagglutination. Auto-immune associated liver disease appeared infrequent. The possibility that the hepatitis B virus is an important cause of cirrhosis in Kenya is discussed. |
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ISSN: | 0035-9203 1878-3503 |
DOI: | 10.1016/0035-9203(76)90130-9 |