Ethylation: Biological Formation of an S-Ethyl Homolog of Lincomycin
Streptomyces umbrinus var. cyaneoniger produces the antibiotic lincomycin. When grown in the presence of ethionine an additional antibiotic is produced. Physical and chemical analyses and incorporation of radioisotopes indicate that the new antibiotic is the S-ethyl homolog of lincomycin.
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Veröffentlicht in: | Science (American Association for the Advancement of Science) 1964-12, Vol.146 (3652), p.1691-1692 |
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container_title | Science (American Association for the Advancement of Science) |
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creator | Patterson, E. L. Hash, J. H. Lincks, M. Miller, P. A. Bohonos, N. |
description | Streptomyces umbrinus var. cyaneoniger produces the antibiotic lincomycin. When grown in the presence of ethionine an additional antibiotic is produced. Physical and chemical analyses and incorporation of radioisotopes indicate that the new antibiotic is the S-ethyl homolog of lincomycin. |
doi_str_mv | 10.1126/science.146.3652.1691 |
format | Article |
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language | eng |
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source | MEDLINE; JSTOR Archive Collection A-Z Listing; American Association for the Advancement of Science |
subjects | Alcoholic beverages Amino Acids - metabolism Anti-Bacterial Agents Antibiotics Chemical bases Ethionine Hydrochlorides Lincomycin Methionine Old Medline Paper chromatography Plant growth Purines RNA Salts Streptomyces |
title | Ethylation: Biological Formation of an S-Ethyl Homolog of Lincomycin |
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