Ethylation: Biological Formation of an S-Ethyl Homolog of Lincomycin

Streptomyces umbrinus var. cyaneoniger produces the antibiotic lincomycin. When grown in the presence of ethionine an additional antibiotic is produced. Physical and chemical analyses and incorporation of radioisotopes indicate that the new antibiotic is the S-ethyl homolog of lincomycin.

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Veröffentlicht in:Science (American Association for the Advancement of Science) 1964-12, Vol.146 (3652), p.1691-1692
Hauptverfasser: Patterson, E. L., Hash, J. H., Lincks, M., Miller, P. A., Bohonos, N.
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container_end_page 1692
container_issue 3652
container_start_page 1691
container_title Science (American Association for the Advancement of Science)
container_volume 146
creator Patterson, E. L.
Hash, J. H.
Lincks, M.
Miller, P. A.
Bohonos, N.
description Streptomyces umbrinus var. cyaneoniger produces the antibiotic lincomycin. When grown in the presence of ethionine an additional antibiotic is produced. Physical and chemical analyses and incorporation of radioisotopes indicate that the new antibiotic is the S-ethyl homolog of lincomycin.
doi_str_mv 10.1126/science.146.3652.1691
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source MEDLINE; JSTOR Archive Collection A-Z Listing; American Association for the Advancement of Science
subjects Alcoholic beverages
Amino Acids - metabolism
Anti-Bacterial Agents
Antibiotics
Chemical bases
Ethionine
Hydrochlorides
Lincomycin
Methionine
Old Medline
Paper chromatography
Plant growth
Purines
RNA
Salts
Streptomyces
title Ethylation: Biological Formation of an S-Ethyl Homolog of Lincomycin
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