2-Aminobenzenethiol Derivatives as Potential Psychotherapeutic Agents II

A similarity between reserpine and the phenothiazine type psychotherapeutic agents is described and illustrated with Stuart-Briegleb molecular models. In an attempt to validate this similarity a series of 2-aminobenzenethiol derivatives was synthesized and screened, resulting in unusual pharmacologi...

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Veröffentlicht in:Journal of pharmaceutical sciences 1964-05, Vol.53 (5), p.529-531
Hauptverfasser: Nieforth, Karl A., Robichaud, Roger C.
Format: Artikel
Sprache:eng
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Zusammenfassung:A similarity between reserpine and the phenothiazine type psychotherapeutic agents is described and illustrated with Stuart-Briegleb molecular models. In an attempt to validate this similarity a series of 2-aminobenzenethiol derivatives was synthesized and screened, resulting in unusual pharmacological properties.
ISSN:0022-3549
1520-6017
DOI:10.1002/jps.2600530515