Intestinal Phosphatase Activity: Acceleration of Increase by Puromycin and Actinomycin
Alkaline phosphatase activity of the mouse duodenum normally increases 20-fold between 13 and 20 days. Activity at 15 days is raised two to three times above normal by administering actinomycin D, puromycin, or the aminonucleoside of puromycin at 13 or 14 days. Phosphatase activity in the jejunum an...
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Veröffentlicht in: | Science (American Association for the Advancement of Science) 1964-04, Vol.144 (3617), p.414-416 |
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creator | Moog, Florence |
description | Alkaline phosphatase activity of the mouse duodenum normally increases 20-fold between 13 and 20 days. Activity at 15 days is raised two to three times above normal by administering actinomycin D, puromycin, or the aminonucleoside of puromycin at 13 or 14 days. Phosphatase activity in the jejunum and kidney are not similarly affected. |
doi_str_mv | 10.1126/science.144.3617.414 |
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Activity at 15 days is raised two to three times above normal by administering actinomycin D, puromycin, or the aminonucleoside of puromycin at 13 or 14 days. Phosphatase activity in the jejunum and kidney are not similarly affected.</description><identifier>ISSN: 0036-8075</identifier><identifier>EISSN: 1095-9203</identifier><identifier>DOI: 10.1126/science.144.3617.414</identifier><identifier>PMID: 14169330</identifier><language>eng</language><publisher>United States: American Association for the Advancement of Science</publisher><subject>Actinomycin ; Alkaline Phosphatase ; Animals ; Anti-Bacterial Agents ; Antibiotics ; Dactinomycin ; Duodenum ; Jejunum ; Kidney ; Kidneys ; Mice ; Molecules ; Nucleosides ; Old Medline ; Pharmacology ; Phenyls ; Phosphatases ; Phosphates ; Pituitary gland ; Puromycin</subject><ispartof>Science (American Association for the Advancement of Science), 1964-04, Vol.144 (3617), p.414-416</ispartof><rights>Copyright 1964 American Association for the Advancement of Science</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c356t-7a9acb0ddf8024a6c7174ac33a3cdb2336f8dc56a81eff6c4d7e369c26279d13</citedby><cites>FETCH-LOGICAL-c356t-7a9acb0ddf8024a6c7174ac33a3cdb2336f8dc56a81eff6c4d7e369c26279d13</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.jstor.org/stable/pdf/1713447$$EPDF$$P50$$Gjstor$$H</linktopdf><linktohtml>$$Uhttps://www.jstor.org/stable/1713447$$EHTML$$P50$$Gjstor$$H</linktohtml><link.rule.ids>314,780,784,803,2882,2883,27923,27924,58016,58249</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/14169330$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Moog, Florence</creatorcontrib><title>Intestinal Phosphatase Activity: Acceleration of Increase by Puromycin and Actinomycin</title><title>Science (American Association for the Advancement of Science)</title><addtitle>Science</addtitle><description>Alkaline phosphatase activity of the mouse duodenum normally increases 20-fold between 13 and 20 days. Activity at 15 days is raised two to three times above normal by administering actinomycin D, puromycin, or the aminonucleoside of puromycin at 13 or 14 days. Phosphatase activity in the jejunum and kidney are not similarly affected.</description><subject>Actinomycin</subject><subject>Alkaline Phosphatase</subject><subject>Animals</subject><subject>Anti-Bacterial Agents</subject><subject>Antibiotics</subject><subject>Dactinomycin</subject><subject>Duodenum</subject><subject>Jejunum</subject><subject>Kidney</subject><subject>Kidneys</subject><subject>Mice</subject><subject>Molecules</subject><subject>Nucleosides</subject><subject>Old Medline</subject><subject>Pharmacology</subject><subject>Phenyls</subject><subject>Phosphatases</subject><subject>Phosphates</subject><subject>Pituitary gland</subject><subject>Puromycin</subject><issn>0036-8075</issn><issn>1095-9203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1964</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkF1LwzAUhoMobk7_wZBeedea9KRJ690QPwYDdzG8DWmaso42nUkq9N-bucKucsJ53sM5D0JLghNCUvbsVKON0gmhNAFGeEIJvUJzgossLlIM12iOMbA4xzyboTvnDhiHXgG3aEYoYQUAnqPvtfHa-cbINtrue3fcSy-djlbKN7-NH19CpXSrrfRNb6K-jtZGWX1CyjHaDrbvRtWYSJrqP2PO_3t0U8vW6YfpXaDd-9vu9TPefH2sX1ebWEHGfMxlIVWJq6rOcUolU5xwKhWABFWVKQCr80plTOZE1zVTtOIaWKFSlvKiIrBAT-exR9v_DOEO0TUurNtKo_vBiRwYZgWHANIzqGzvnNW1ONqmk3YUBIuTTjHpFEGnOOkUQWeIPU7zh7LT1SU0-QvA8gwcnO_tpc8JUMrhD6HOfYM</recordid><startdate>19640424</startdate><enddate>19640424</enddate><creator>Moog, Florence</creator><general>American Association for the Advancement of Science</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19640424</creationdate><title>Intestinal Phosphatase Activity: Acceleration of Increase by Puromycin and Actinomycin</title><author>Moog, Florence</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c356t-7a9acb0ddf8024a6c7174ac33a3cdb2336f8dc56a81eff6c4d7e369c26279d13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1964</creationdate><topic>Actinomycin</topic><topic>Alkaline Phosphatase</topic><topic>Animals</topic><topic>Anti-Bacterial Agents</topic><topic>Antibiotics</topic><topic>Dactinomycin</topic><topic>Duodenum</topic><topic>Jejunum</topic><topic>Kidney</topic><topic>Kidneys</topic><topic>Mice</topic><topic>Molecules</topic><topic>Nucleosides</topic><topic>Old Medline</topic><topic>Pharmacology</topic><topic>Phenyls</topic><topic>Phosphatases</topic><topic>Phosphates</topic><topic>Pituitary gland</topic><topic>Puromycin</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Moog, Florence</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Science (American Association for the Advancement of Science)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Moog, Florence</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Intestinal Phosphatase Activity: Acceleration of Increase by Puromycin and Actinomycin</atitle><jtitle>Science (American Association for the Advancement of Science)</jtitle><addtitle>Science</addtitle><date>1964-04-24</date><risdate>1964</risdate><volume>144</volume><issue>3617</issue><spage>414</spage><epage>416</epage><pages>414-416</pages><issn>0036-8075</issn><eissn>1095-9203</eissn><abstract>Alkaline phosphatase activity of the mouse duodenum normally increases 20-fold between 13 and 20 days. Activity at 15 days is raised two to three times above normal by administering actinomycin D, puromycin, or the aminonucleoside of puromycin at 13 or 14 days. Phosphatase activity in the jejunum and kidney are not similarly affected.</abstract><cop>United States</cop><pub>American Association for the Advancement of Science</pub><pmid>14169330</pmid><doi>10.1126/science.144.3617.414</doi><tpages>3</tpages></addata></record> |
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source | MEDLINE; JSTOR Archive Collection A-Z Listing; American Association for the Advancement of Science |
subjects | Actinomycin Alkaline Phosphatase Animals Anti-Bacterial Agents Antibiotics Dactinomycin Duodenum Jejunum Kidney Kidneys Mice Molecules Nucleosides Old Medline Pharmacology Phenyls Phosphatases Phosphates Pituitary gland Puromycin |
title | Intestinal Phosphatase Activity: Acceleration of Increase by Puromycin and Actinomycin |
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