Intestinal Phosphatase Activity: Acceleration of Increase by Puromycin and Actinomycin

Alkaline phosphatase activity of the mouse duodenum normally increases 20-fold between 13 and 20 days. Activity at 15 days is raised two to three times above normal by administering actinomycin D, puromycin, or the aminonucleoside of puromycin at 13 or 14 days. Phosphatase activity in the jejunum an...

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Veröffentlicht in:Science (American Association for the Advancement of Science) 1964-04, Vol.144 (3617), p.414-416
1. Verfasser: Moog, Florence
Format: Artikel
Sprache:eng
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Zusammenfassung:Alkaline phosphatase activity of the mouse duodenum normally increases 20-fold between 13 and 20 days. Activity at 15 days is raised two to three times above normal by administering actinomycin D, puromycin, or the aminonucleoside of puromycin at 13 or 14 days. Phosphatase activity in the jejunum and kidney are not similarly affected.
ISSN:0036-8075
1095-9203
DOI:10.1126/science.144.3617.414