Digestion of amidinated and phenylglyoxal treated fibrinogen by plasmin

Digestion of amidinated and phenylglyoxal treated fibrinogen by plasmin

Human fibrinogen with the lysyl and/or arginyl residues modified by treatment with ethyl acetimidate hydrochloride and phenylglyoxal monohydrate, respectively, was incubated with plasmin. Both chemical modifications delayed the appearance of components Y, D and E while component X was not affected.

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Bibliographische Detailangaben
Veröffentlicht in:Thrombosis research 1976-09, Vol.9 (3), p.261-266
Hauptverfasser: Kang, Edward P., Triantaphyllopoulos, Demetrios C.
Format: Artikel
Sprache:eng
Schlagworte:
Amidines
Electrophoresis, Polyacrylamide Gel
Fibrinogen - metabolism
Fibrinolysin - metabolism
Glyoxal
Humans
Peptides - analysis
Time Factors
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Beschreibung
Zusammenfassung:Human fibrinogen with the lysyl and/or arginyl residues modified by treatment with ethyl acetimidate hydrochloride and phenylglyoxal monohydrate, respectively, was incubated with plasmin. Both chemical modifications delayed the appearance of components Y, D and E while component X was not affected.
ISSN:0049-3848
1879-2472
DOI:10.1016/0049-3848(76)90215-2