Canine leishmaniasis with amyloidosis
Visceral leishmaniasis was diagnosed in a 2-year-old male Great Dane imported from Greece. The clinical signs included anemia, diarrhea, weight loss, proteinuria, and hyperglobulinemia with increases in α2- and γ-regions. At necropsy there was plasmalymphocytic and macrophage infiltration of spleen,...
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Veröffentlicht in: | Veterinary pathology 1976-01, Vol.13 (5), p.365-373 |
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creator | George, J.W Nielsen, S.W Shiverly, J.N Hopek, S Mroz, S |
description | Visceral leishmaniasis was diagnosed in a 2-year-old male Great Dane imported from Greece. The clinical signs included anemia, diarrhea, weight loss, proteinuria, and hyperglobulinemia with increases in α2- and γ-regions. At necropsy there was plasmalymphocytic and macrophage infiltration of spleen, macrophage infiltration of bone marrow, intracellular organisms of macrophages having the ultrastructural characteristics of Leishmania species, and severe amyloidosis of the spleen, liver, and kidney. |
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The clinical signs included anemia, diarrhea, weight loss, proteinuria, and hyperglobulinemia with increases in α2- and γ-regions. At necropsy there was plasmalymphocytic and macrophage infiltration of spleen, macrophage infiltration of bone marrow, intracellular organisms of macrophages having the ultrastructural characteristics of Leishmania species, and severe amyloidosis of the spleen, liver, and kidney.</description><identifier>ISSN: 0300-9858</identifier><identifier>EISSN: 1544-2217</identifier><identifier>DOI: 10.1177/030098587601300506</identifier><identifier>PMID: 982752</identifier><language>eng</language><publisher>Los Angeles, CA: SAGE Publications</publisher><subject>Amyloidosis - complications ; Amyloidosis - veterinary ; Animals ; Dog Diseases - parasitology ; Dogs ; Leishmania donovani ; Leishmaniasis, Visceral - complications ; Leishmaniasis, Visceral - parasitology ; Leishmaniasis, Visceral - veterinary ; Macrophages - parasitology ; Male ; Phlebotomus ; Spleen - pathology</subject><ispartof>Veterinary pathology, 1976-01, Vol.13 (5), p.365-373</ispartof><rights>1976 American College of Veterinary Pathologists</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c405t-81038ff8240c4132dcadaf65dfbcd8faed79f7fed92e7953063945cea352a2443</citedby><cites>FETCH-LOGICAL-c405t-81038ff8240c4132dcadaf65dfbcd8faed79f7fed92e7953063945cea352a2443</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://journals.sagepub.com/doi/pdf/10.1177/030098587601300506$$EPDF$$P50$$Gsage$$H</linktopdf><linktohtml>$$Uhttps://journals.sagepub.com/doi/10.1177/030098587601300506$$EHTML$$P50$$Gsage$$H</linktohtml><link.rule.ids>314,776,780,21798,27901,27902,43597,43598</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/982752$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>George, J.W</creatorcontrib><creatorcontrib>Nielsen, S.W</creatorcontrib><creatorcontrib>Shiverly, J.N</creatorcontrib><creatorcontrib>Hopek, S</creatorcontrib><creatorcontrib>Mroz, S</creatorcontrib><title>Canine leishmaniasis with amyloidosis</title><title>Veterinary pathology</title><addtitle>Vet Pathol</addtitle><description>Visceral leishmaniasis was diagnosed in a 2-year-old male Great Dane imported from Greece. The clinical signs included anemia, diarrhea, weight loss, proteinuria, and hyperglobulinemia with increases in α2- and γ-regions. At necropsy there was plasmalymphocytic and macrophage infiltration of spleen, macrophage infiltration of bone marrow, intracellular organisms of macrophages having the ultrastructural characteristics of Leishmania species, and severe amyloidosis of the spleen, liver, and kidney.</description><subject>Amyloidosis - complications</subject><subject>Amyloidosis - veterinary</subject><subject>Animals</subject><subject>Dog Diseases - parasitology</subject><subject>Dogs</subject><subject>Leishmania donovani</subject><subject>Leishmaniasis, Visceral - complications</subject><subject>Leishmaniasis, Visceral - parasitology</subject><subject>Leishmaniasis, Visceral - veterinary</subject><subject>Macrophages - parasitology</subject><subject>Male</subject><subject>Phlebotomus</subject><subject>Spleen - pathology</subject><issn>0300-9858</issn><issn>1544-2217</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1976</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kEtLAzEUhYP4qtU_IILd6G5snpNkKcUXFFxo1yHNo02ZR006SP-9Gaa4EVzdyz3fOXAPANcIPiDE-RQSCKVggpcQ5ZXB8giMEKO0wBjxYzDqgaInzsFFShsIMZaCn4FTKTBneATuZroJjZtULqR1nXedQpp8h916out91Qbb5sMlOPG6Su7qMMdg8fz0OXst5u8vb7PHeWEoZLtCIEiE9wJTaCgi2BpttS-Z9UtjhdfOcum5d1ZixyUjsCSSMuM0YVhjSskY3A-529h-dS7tVB2ScVWlG9d2SQnCJIVCZhAPoIltStF5tY2h1nGvEFR9NepvNdl0c0jvlrWzv5ahiyxPBznplVObtotN_vX_wNvB4XWr9CqGpBYfuJdzy5JwRH4AX_h0AQ</recordid><startdate>19760101</startdate><enddate>19760101</enddate><creator>George, J.W</creator><creator>Nielsen, S.W</creator><creator>Shiverly, J.N</creator><creator>Hopek, S</creator><creator>Mroz, S</creator><general>SAGE Publications</general><scope>FBQ</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19760101</creationdate><title>Canine leishmaniasis with amyloidosis</title><author>George, J.W ; Nielsen, S.W ; Shiverly, J.N ; Hopek, S ; Mroz, S</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c405t-81038ff8240c4132dcadaf65dfbcd8faed79f7fed92e7953063945cea352a2443</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1976</creationdate><topic>Amyloidosis - complications</topic><topic>Amyloidosis - veterinary</topic><topic>Animals</topic><topic>Dog Diseases - parasitology</topic><topic>Dogs</topic><topic>Leishmania donovani</topic><topic>Leishmaniasis, Visceral - complications</topic><topic>Leishmaniasis, Visceral - parasitology</topic><topic>Leishmaniasis, Visceral - veterinary</topic><topic>Macrophages - parasitology</topic><topic>Male</topic><topic>Phlebotomus</topic><topic>Spleen - pathology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>George, J.W</creatorcontrib><creatorcontrib>Nielsen, S.W</creatorcontrib><creatorcontrib>Shiverly, J.N</creatorcontrib><creatorcontrib>Hopek, S</creatorcontrib><creatorcontrib>Mroz, S</creatorcontrib><collection>AGRIS</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Veterinary pathology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>George, J.W</au><au>Nielsen, S.W</au><au>Shiverly, J.N</au><au>Hopek, S</au><au>Mroz, S</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Canine leishmaniasis with amyloidosis</atitle><jtitle>Veterinary pathology</jtitle><addtitle>Vet Pathol</addtitle><date>1976-01-01</date><risdate>1976</risdate><volume>13</volume><issue>5</issue><spage>365</spage><epage>373</epage><pages>365-373</pages><issn>0300-9858</issn><eissn>1544-2217</eissn><abstract>Visceral leishmaniasis was diagnosed in a 2-year-old male Great Dane imported from Greece. The clinical signs included anemia, diarrhea, weight loss, proteinuria, and hyperglobulinemia with increases in α2- and γ-regions. At necropsy there was plasmalymphocytic and macrophage infiltration of spleen, macrophage infiltration of bone marrow, intracellular organisms of macrophages having the ultrastructural characteristics of Leishmania species, and severe amyloidosis of the spleen, liver, and kidney.</abstract><cop>Los Angeles, CA</cop><pub>SAGE Publications</pub><pmid>982752</pmid><doi>10.1177/030098587601300506</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Amyloidosis - complications Amyloidosis - veterinary Animals Dog Diseases - parasitology Dogs Leishmania donovani Leishmaniasis, Visceral - complications Leishmaniasis, Visceral - parasitology Leishmaniasis, Visceral - veterinary Macrophages - parasitology Male Phlebotomus Spleen - pathology |
title | Canine leishmaniasis with amyloidosis |
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