Canine leishmaniasis with amyloidosis

Visceral leishmaniasis was diagnosed in a 2-year-old male Great Dane imported from Greece. The clinical signs included anemia, diarrhea, weight loss, proteinuria, and hyperglobulinemia with increases in α2- and γ-regions. At necropsy there was plasmalymphocytic and macrophage infiltration of spleen,...

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Veröffentlicht in:Veterinary pathology 1976-01, Vol.13 (5), p.365-373
Hauptverfasser: George, J.W, Nielsen, S.W, Shiverly, J.N, Hopek, S, Mroz, S
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container_title Veterinary pathology
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creator George, J.W
Nielsen, S.W
Shiverly, J.N
Hopek, S
Mroz, S
description Visceral leishmaniasis was diagnosed in a 2-year-old male Great Dane imported from Greece. The clinical signs included anemia, diarrhea, weight loss, proteinuria, and hyperglobulinemia with increases in α2- and γ-regions. At necropsy there was plasmalymphocytic and macrophage infiltration of spleen, macrophage infiltration of bone marrow, intracellular organisms of macrophages having the ultrastructural characteristics of Leishmania species, and severe amyloidosis of the spleen, liver, and kidney.
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subjects Amyloidosis - complications
Amyloidosis - veterinary
Animals
Dog Diseases - parasitology
Dogs
Leishmania donovani
Leishmaniasis, Visceral - complications
Leishmaniasis, Visceral - parasitology
Leishmaniasis, Visceral - veterinary
Macrophages - parasitology
Male
Phlebotomus
Spleen - pathology
title Canine leishmaniasis with amyloidosis
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