Erythrocyte Glutathione-levels in Patients of a Mental Hospital
THE work of Beutler 1 on erythrocyte glutathione ‘instability’ has demonstrated the significance of the glutathione content of red cells for the maintenance of overall erythrocyte structure (and presumably function). In addition, Rigas et al. 2 have shown how the interaction of hæmoglobin and oxidiz...
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Veröffentlicht in: | Nature (London) 1964-05, Vol.202 (4935), p.904-904 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | THE work of Beutler
1
on erythrocyte glutathione ‘instability’ has demonstrated the significance of the glutathione content of red cells for the maintenance of overall erythrocyte structure (and presumably function). In addition, Rigas
et al.
2
have shown how the interaction of hæmoglobin and oxidized glutathione can lead to increased rates of splenic erythrocyte destruction. A number of disease states have been related to increased instability of erythrocyte glutathione; for example, Theil
et al.
3
have shown a significant decrease of blood glutathione-levels in patients with acute renal insufficiency. |
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ISSN: | 0028-0836 1476-4687 |
DOI: | 10.1038/202904a0 |