Nucleic Acid Metabolism in L Cells Infected with a Member of the Psittacosis Group

Nucleic Acid Metabolism in L Cells Infected with a Member of the Psittacosis Group

Multiplication of the meningopneumonitis agent in the cytoplasm of L cells in suspension culture is accompanied by parallel increases in cytoplasmic DNA, RNA, and phospholipid. Synthesis of RNA and phospholipid in infected cells is inhibited at the height of meningopneumonitis multiplication, but nu...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Science (American Association for the Advancement of Science) 1964-08, Vol.145 (3634), p.819-821
Hauptverfasser: Schechter, Esther M., Ilse I. E. Tribby, Moulder, James W.
Format: Artikel
Sprache:eng
Schlagworte:
Autoradiography
Cell nucleus
Cellular metabolism
Chlamydophila psittaci
Cultured cells
Cytoplasm
DNA
DNA, Viral
Infections
L cells
Lipid Metabolism
Metabolism
Mice
Nucleic acids
Old Medline
Parasite hosts
Phospholipids
Phosphorus Isotopes
Psittacosis
RNA
RNA, Viral
Tissue Culture Techniques
Virus Cultivation
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Multiplication of the meningopneumonitis agent in the cytoplasm of L cells in suspension culture is accompanied by parallel increases in cytoplasmic DNA, RNA, and phospholipid. Synthesis of RNA and phospholipid in infected cells is inhibited at the height of meningopneumonitis multiplication, but nuclear DNA synthesis is inhibited earlier and to a greater degree.
ISSN:0036-8075
1095-9203
DOI:10.1126/science.145.3634.819