Uricase: Localization in Hepatic Microbodies

Microbodies of rat hepatic cells and hepatomas contain a crystalloid with the same structural characteristics as crystals of purified uricase, when viewed by electron microscopy. We conclude that crystalline uricase is located within hepatic microbodies.

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Veröffentlicht in:Science (American Association for the Advancement of Science) 1964-12, Vol.146 (3649), p.1316-1318
Hauptverfasser: Hruban, Zdenek, Swift, Hewson
Format: Artikel
Sprache:eng
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Zusammenfassung:Microbodies of rat hepatic cells and hepatomas contain a crystalloid with the same structural characteristics as crystals of purified uricase, when viewed by electron microscopy. We conclude that crystalline uricase is located within hepatic microbodies.
ISSN:0036-8075
1095-9203
DOI:10.1126/science.146.3649.1316