Nucleolar Aberrations in Frog Kidney Tumour Cells

ACCORDING to Gates 1 , the nucleolus was apparently the first intranuclear organelle described; yet its function in the normal cell has never been fully clarified 2 , nor has its possible malfunction in malignant cells 3,4 . But Caspersson 5 has held that chromatin associated with the nucleolus and...

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Veröffentlicht in:Nature (London) 1964-02, Vol.201 (4921), p.840-841
Hauptverfasser: NORDSIEK, FREDERIC W., KOPAC, M. J.
Format: Artikel
Sprache:eng
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Zusammenfassung:ACCORDING to Gates 1 , the nucleolus was apparently the first intranuclear organelle described; yet its function in the normal cell has never been fully clarified 2 , nor has its possible malfunction in malignant cells 3,4 . But Caspersson 5 has held that chromatin associated with the nucleolus and the genes which govern its function must play a part in carcinogenesis.
ISSN:0028-0836
1476-4687
DOI:10.1038/201840a0