Preparation of Tri- and Tetramethyleneisoxazoles
The syntheses of several tri‐ and tetramethyleneisoxazoles resulting from the condensation of C(α)O‐dilithioximes with esters, followed by acid cyclization, are described.
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Veröffentlicht in: | Journal of pharmaceutical sciences 1976-09, Vol.65 (9), p.1408-1409 |
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container_title | Journal of pharmaceutical sciences |
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creator | Beam, Charles F. Shealy, Keith D. Harris, Charles E. Shealy, Neal L. Dasher, Luther W. Hollinger, Wayne M. Sandifer, Ronda M. Reames, David C. |
description | The syntheses of several tri‐ and tetramethyleneisoxazoles resulting from the condensation of C(α)O‐dilithioximes with esters, followed by acid cyclization, are described. |
doi_str_mv | 10.1002/jps.2600650939 |
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Pharm. Sci</addtitle><description>The syntheses of several tri‐ and tetramethyleneisoxazoles resulting from the condensation of C(α)O‐dilithioximes with esters, followed by acid cyclization, are described.</description><subject>4-dianions with esters followed by acid cyclization</subject><subject>Cyclization</subject><subject>Isoxazoles</subject><subject>Isoxazoles - chemical synthesis</subject><subject>Isoxazoles, tri‐ and tetramethylene—synthesized by condensation of 1,4‐dianions with esters followed by acid cyclization</subject><subject>Oxazoles - chemical synthesis</subject><subject>tri- and tetramethylene-synthesized by condensation of 1</subject><subject>Tri- and tetramethyleneisoxazoles-synthesized by condensation of 1</subject><subject>Tri‐ and tetramethyleneisoxazoles—synthesized by condensation of 1,4‐dianions with esters followed by acid cyclization</subject><issn>0022-3549</issn><issn>1520-6017</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1976</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkDtPwzAUhS3EqxRWJoZObCl-JI49IsRTFRQRYLQc-0YY0qTYKVB-PUZBIAbEdIfznSPdD6FdgscEY3rwOA9jyjHmGZZMrqAByShOOCb5KhpEgCYsS-Um2grhEUcMZ9kGWpecE84HCE89zLXXnWubUVuNCu-SkW7sqIDO6xl0D8saGnChfdPvbQ1hG61Vug6w83WH6PbkuDg6SyZXp-dHh5PEsJTIRGABllCiS2twqVNqSmkIBSoFZJbwnJaapwLL1FaEMMNzsIxTXUrBOM8rNkT7_e7ct88LCJ2auWCgrnUD7SIoEb_CacojOO5B49sQPFRq7t1M-6UiWH0aUtGQ-jEUC3tfy4tyBvYb75XEWPbxq6th-c-Yupje_JpO-q4LHbx9d7V_UjxneabuL0-VuL4riqlgikRe9DxEky8OvArGQWPAOg-mU7Z1f33xAdBekyY</recordid><startdate>197609</startdate><enddate>197609</enddate><creator>Beam, Charles F.</creator><creator>Shealy, Keith D.</creator><creator>Harris, Charles E.</creator><creator>Shealy, Neal L.</creator><creator>Dasher, Luther W.</creator><creator>Hollinger, Wayne M.</creator><creator>Sandifer, Ronda M.</creator><creator>Reames, David C.</creator><general>Elsevier Inc</general><general>Wiley Subscription Services, Inc., A Wiley Company</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>197609</creationdate><title>Preparation of Tri- and Tetramethyleneisoxazoles</title><author>Beam, Charles F. ; Shealy, Keith D. ; Harris, Charles E. ; Shealy, Neal L. ; Dasher, Luther W. ; Hollinger, Wayne M. ; Sandifer, Ronda M. ; Reames, David C.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3419-808ed121abdc0ba42cb9c12e298e5d1672ba648094df113c67ed362ab983667f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1976</creationdate><topic>4-dianions with esters followed by acid cyclization</topic><topic>Cyclization</topic><topic>Isoxazoles</topic><topic>Isoxazoles - chemical synthesis</topic><topic>Isoxazoles, tri‐ and tetramethylene—synthesized by condensation of 1,4‐dianions with esters followed by acid cyclization</topic><topic>Oxazoles - chemical synthesis</topic><topic>tri- and tetramethylene-synthesized by condensation of 1</topic><topic>Tri- and tetramethyleneisoxazoles-synthesized by condensation of 1</topic><topic>Tri‐ and tetramethyleneisoxazoles—synthesized by condensation of 1,4‐dianions with esters followed by acid cyclization</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Beam, Charles F.</creatorcontrib><creatorcontrib>Shealy, Keith D.</creatorcontrib><creatorcontrib>Harris, Charles E.</creatorcontrib><creatorcontrib>Shealy, Neal L.</creatorcontrib><creatorcontrib>Dasher, Luther W.</creatorcontrib><creatorcontrib>Hollinger, Wayne M.</creatorcontrib><creatorcontrib>Sandifer, Ronda M.</creatorcontrib><creatorcontrib>Reames, David C.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of pharmaceutical sciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Beam, Charles F.</au><au>Shealy, Keith D.</au><au>Harris, Charles E.</au><au>Shealy, Neal L.</au><au>Dasher, Luther W.</au><au>Hollinger, Wayne M.</au><au>Sandifer, Ronda M.</au><au>Reames, David C.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Preparation of Tri- and Tetramethyleneisoxazoles</atitle><jtitle>Journal of pharmaceutical sciences</jtitle><addtitle>J. Pharm. Sci</addtitle><date>1976-09</date><risdate>1976</risdate><volume>65</volume><issue>9</issue><spage>1408</spage><epage>1409</epage><pages>1408-1409</pages><issn>0022-3549</issn><eissn>1520-6017</eissn><abstract>The syntheses of several tri‐ and tetramethyleneisoxazoles resulting from the condensation of C(α)O‐dilithioximes with esters, followed by acid cyclization, are described.</abstract><cop>Washington</cop><pub>Elsevier Inc</pub><pmid>966166</pmid><doi>10.1002/jps.2600650939</doi><tpages>2</tpages></addata></record> |
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ispartof | Journal of pharmaceutical sciences, 1976-09, Vol.65 (9), p.1408-1409 |
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language | eng |
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source | MEDLINE; Access via Wiley Online Library; Alma/SFX Local Collection |
subjects | 4-dianions with esters followed by acid cyclization Cyclization Isoxazoles Isoxazoles - chemical synthesis Isoxazoles, tri‐ and tetramethylene—synthesized by condensation of 1,4‐dianions with esters followed by acid cyclization Oxazoles - chemical synthesis tri- and tetramethylene-synthesized by condensation of 1 Tri- and tetramethyleneisoxazoles-synthesized by condensation of 1 Tri‐ and tetramethyleneisoxazoles—synthesized by condensation of 1,4‐dianions with esters followed by acid cyclization |
title | Preparation of Tri- and Tetramethyleneisoxazoles |
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