Preparation of Tri- and Tetramethyleneisoxazoles

The syntheses of several tri‐ and tetramethyleneisoxazoles resulting from the condensation of C(α)O‐dilithioximes with esters, followed by acid cyclization, are described.

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Veröffentlicht in:Journal of pharmaceutical sciences 1976-09, Vol.65 (9), p.1408-1409
Hauptverfasser: Beam, Charles F., Shealy, Keith D., Harris, Charles E., Shealy, Neal L., Dasher, Luther W., Hollinger, Wayne M., Sandifer, Ronda M., Reames, David C.
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container_end_page 1409
container_issue 9
container_start_page 1408
container_title Journal of pharmaceutical sciences
container_volume 65
creator Beam, Charles F.
Shealy, Keith D.
Harris, Charles E.
Shealy, Neal L.
Dasher, Luther W.
Hollinger, Wayne M.
Sandifer, Ronda M.
Reames, David C.
description The syntheses of several tri‐ and tetramethyleneisoxazoles resulting from the condensation of C(α)O‐dilithioximes with esters, followed by acid cyclization, are described.
doi_str_mv 10.1002/jps.2600650939
format Article
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identifier ISSN: 0022-3549
ispartof Journal of pharmaceutical sciences, 1976-09, Vol.65 (9), p.1408-1409
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language eng
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source MEDLINE; Access via Wiley Online Library; Alma/SFX Local Collection
subjects 4-dianions with esters followed by acid cyclization
Cyclization
Isoxazoles
Isoxazoles - chemical synthesis
Isoxazoles, tri‐ and tetramethylene—synthesized by condensation of 1,4‐dianions with esters followed by acid cyclization
Oxazoles - chemical synthesis
tri- and tetramethylene-synthesized by condensation of 1
Tri- and tetramethyleneisoxazoles-synthesized by condensation of 1
Tri‐ and tetramethyleneisoxazoles—synthesized by condensation of 1,4‐dianions with esters followed by acid cyclization
title Preparation of Tri- and Tetramethyleneisoxazoles
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