Preparation of Tri- and Tetramethyleneisoxazoles

The syntheses of several tri‐ and tetramethyleneisoxazoles resulting from the condensation of C(α)O‐dilithioximes with esters, followed by acid cyclization, are described.

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Bibliographische Detailangaben
Veröffentlicht in:	Journal of pharmaceutical sciences 1976-09, Vol.65 (9), p.1408-1409
Hauptverfasser:	Beam, Charles F., Shealy, Keith D., Harris, Charles E., Shealy, Neal L., Dasher, Luther W., Hollinger, Wayne M., Sandifer, Ronda M., Reames, David C.
Format:	Artikel
Sprache:	eng
Schlagworte:	4-dianions with esters followed by acid cyclization Cyclization Isoxazoles Isoxazoles - chemical synthesis Isoxazoles, tri‐ and tetramethylene—synthesized by condensation of 1,4‐dianions with esters followed by acid cyclization Oxazoles - chemical synthesis tri- and tetramethylene-synthesized by condensation of 1 Tri- and tetramethyleneisoxazoles-synthesized by condensation of 1 Tri‐ and tetramethyleneisoxazoles—synthesized by condensation of 1,4‐dianions with esters followed by acid cyclization
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Beschreibung
Zusammenfassung:	The syntheses of several tri‐ and tetramethyleneisoxazoles resulting from the condensation of C(α)O‐dilithioximes with esters, followed by acid cyclization, are described.
ISSN:	0022-3549 1520-6017
DOI:	10.1002/jps.2600650939