THE STRUCTURE OF ANTIBIOTIC G-52, A NEW AMINOCYCLITOL-AMINOGLYCOSIDE ANTIBIOTIC PRODUCED BY MICROMONOSPORA ZIONENSIS

THE STRUCTURE OF ANTIBIOTIC G-52, A NEW AMINOCYCLITOL-AMINOGLYCOSIDE ANTIBIOTIC PRODUCED BY MICROMONOSPORA ZIONENSIS

Antibiotic G-52, a new aminocyclitol-aminoglycoside antibiotic produced in the fermentation of Micronionospora zionensis, has been shown to be 6'-N-methylsisomicin on the basis of its spectral characteristics. This assignment was confirmed by synthesis of the antibiotic from sisomicin.

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Veröffentlicht in:Journal of antibiotics 1976, Vol.29(5), pp.488-491
Hauptverfasser: DANIELS, PETER J. L., JARET, ROBERT S., NAGABHUSHAN, T. L., TURNER, W. N.
Format: Artikel
Sprache:eng
Schlagworte:
Anti-Bacterial Agents - analogs & derivatives
Chemical Phenomena
Chemistry
Methylation
Micromonospora - metabolism
Sisomicin - analogs & derivatives
Sisomicin - analysis
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Zusammenfassung:Antibiotic G-52, a new aminocyclitol-aminoglycoside antibiotic produced in the fermentation of Micronionospora zionensis, has been shown to be 6'-N-methylsisomicin on the basis of its spectral characteristics. This assignment was confirmed by synthesis of the antibiotic from sisomicin.
ISSN:0021-8820
1881-1469
DOI:10.7164/antibiotics.29.488