Enhancement of Metastatic Calcification Produced with Parathyroid Extract by Parathyroidectomy and Adrenalectomy
Summary Groups of rats were injected with 150 units of bovine PTE over 28 hours. At the end of experiment they were injected intravenously with a standard dose of Ca45Cl2. The extent of the calcific changes was judged from von Kossa stained sections and from concentrations of Ca45/mg tissue. Strikin...
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| Veröffentlicht in: | Experimental biology and medicine (Maywood, N.J.) N.J.), 1963-12, Vol.114 (3), p.714-718 |
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| container_issue | 3 |
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| container_title | Experimental biology and medicine (Maywood, N.J.) |
| container_volume | 114 |
| creator | Stoerk, Herbert C. Celozzi, Evemarie |
| description | Summary
Groups of rats were injected with 150 units of bovine PTE over 28 hours. At the end of experiment they were injected intravenously with a standard dose of Ca45Cl2. The extent of the calcific changes was judged from von Kossa stained sections and from concentrations of Ca45/mg tissue. Striking enhancement of metastatic calcifications was observed in parathyroidectomized and in adrenalectomized rats. DOCA and hydrocortisone prevented the appearance of the calcific changes in adrenalectomized rats. |
| doi_str_mv | 10.3181/00379727-114-28778 |
| format | Article |
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Groups of rats were injected with 150 units of bovine PTE over 28 hours. At the end of experiment they were injected intravenously with a standard dose of Ca45Cl2. The extent of the calcific changes was judged from von Kossa stained sections and from concentrations of Ca45/mg tissue. Striking enhancement of metastatic calcifications was observed in parathyroidectomized and in adrenalectomized rats. DOCA and hydrocortisone prevented the appearance of the calcific changes in adrenalectomized rats.</description><identifier>ISSN: 0037-9727</identifier><identifier>ISSN: 1535-3702</identifier><identifier>EISSN: 1535-3699</identifier><identifier>DOI: 10.3181/00379727-114-28778</identifier><identifier>PMID: 14120332</identifier><language>eng</language><publisher>London, England: SAGE Publications</publisher><subject>Adrenalectomy ; Calcification, Physiologic ; Calcinosis ; Calcium Isotopes ; Desoxycorticosterone ; Hydrocortisone ; Kidney ; Myocardium ; Old Medline ; Parathyroid Glands ; Parathyroid Hormone ; Parathyroidectomy ; Physiology ; Rats ; Tissue Extracts</subject><ispartof>Experimental biology and medicine (Maywood, N.J.), 1963-12, Vol.114 (3), p.714-718</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/14120332$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Stoerk, Herbert C.</creatorcontrib><creatorcontrib>Celozzi, Evemarie</creatorcontrib><title>Enhancement of Metastatic Calcification Produced with Parathyroid Extract by Parathyroidectomy and Adrenalectomy</title><title>Experimental biology and medicine (Maywood, N.J.)</title><addtitle>Proc Soc Exp Biol Med</addtitle><description>Summary
Groups of rats were injected with 150 units of bovine PTE over 28 hours. At the end of experiment they were injected intravenously with a standard dose of Ca45Cl2. The extent of the calcific changes was judged from von Kossa stained sections and from concentrations of Ca45/mg tissue. Striking enhancement of metastatic calcifications was observed in parathyroidectomized and in adrenalectomized rats. DOCA and hydrocortisone prevented the appearance of the calcific changes in adrenalectomized rats.</description><subject>Adrenalectomy</subject><subject>Calcification, Physiologic</subject><subject>Calcinosis</subject><subject>Calcium Isotopes</subject><subject>Desoxycorticosterone</subject><subject>Hydrocortisone</subject><subject>Kidney</subject><subject>Myocardium</subject><subject>Old Medline</subject><subject>Parathyroid Glands</subject><subject>Parathyroid Hormone</subject><subject>Parathyroidectomy</subject><subject>Physiology</subject><subject>Rats</subject><subject>Tissue Extracts</subject><issn>0037-9727</issn><issn>1535-3702</issn><issn>1535-3699</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1963</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kDFv2zAQhYkiQe2k_QMZCk7ZlPBIyZRGw3DaAi6SIZkJ6nSsZUiiS1Jo_O8r1w7SqdPhHr73ho-xGxB3Ckq4F0LpSkudAeSZLLUuP7A5FKrI1KKqLtj8CGRHYsauYtwJAYWWi49sBjlIoZScs_162NoBqachce_4D0o2Jpta5CvbYetanB4_8KfgmxGp4b_btOVPNti0PQTfNnz9moLFxOvDvzFh8v2B26HhyybQYLtT8oldOttF-ny-1-zlYf28-pZtHr9-Xy03GcpKpmyBiFRWpF2TF7rOlSxdqXNXokZdkASQRLWl3GENoBVosHW1cFSRANRCXbPb0-4--F8jxWT6NiJ1nR3Ij9GUqpBFBWoC5QnE4GMM5Mw-tL0NBwPCHD2bN89m8mz-ep5KX87rY91T8145i52A-xMQ7U8yOz-GyUD83-QfmYyIyA</recordid><startdate>196312</startdate><enddate>196312</enddate><creator>Stoerk, Herbert C.</creator><creator>Celozzi, Evemarie</creator><general>SAGE Publications</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>196312</creationdate><title>Enhancement of Metastatic Calcification Produced with Parathyroid Extract by Parathyroidectomy and Adrenalectomy</title><author>Stoerk, Herbert C. ; Celozzi, Evemarie</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c292t-6ccce89e7fd457b4328f874f8c7c75e2112eebae4fcb1173171ab96fe9e01c703</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1963</creationdate><topic>Adrenalectomy</topic><topic>Calcification, Physiologic</topic><topic>Calcinosis</topic><topic>Calcium Isotopes</topic><topic>Desoxycorticosterone</topic><topic>Hydrocortisone</topic><topic>Kidney</topic><topic>Myocardium</topic><topic>Old Medline</topic><topic>Parathyroid Glands</topic><topic>Parathyroid Hormone</topic><topic>Parathyroidectomy</topic><topic>Physiology</topic><topic>Rats</topic><topic>Tissue Extracts</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Stoerk, Herbert C.</creatorcontrib><creatorcontrib>Celozzi, Evemarie</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Experimental biology and medicine (Maywood, N.J.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Stoerk, Herbert C.</au><au>Celozzi, Evemarie</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Enhancement of Metastatic Calcification Produced with Parathyroid Extract by Parathyroidectomy and Adrenalectomy</atitle><jtitle>Experimental biology and medicine (Maywood, N.J.)</jtitle><addtitle>Proc Soc Exp Biol Med</addtitle><date>1963-12</date><risdate>1963</risdate><volume>114</volume><issue>3</issue><spage>714</spage><epage>718</epage><pages>714-718</pages><issn>0037-9727</issn><issn>1535-3702</issn><eissn>1535-3699</eissn><abstract>Summary
Groups of rats were injected with 150 units of bovine PTE over 28 hours. At the end of experiment they were injected intravenously with a standard dose of Ca45Cl2. The extent of the calcific changes was judged from von Kossa stained sections and from concentrations of Ca45/mg tissue. Striking enhancement of metastatic calcifications was observed in parathyroidectomized and in adrenalectomized rats. DOCA and hydrocortisone prevented the appearance of the calcific changes in adrenalectomized rats.</abstract><cop>London, England</cop><pub>SAGE Publications</pub><pmid>14120332</pmid><doi>10.3181/00379727-114-28778</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0037-9727 |
| ispartof | Experimental biology and medicine (Maywood, N.J.), 1963-12, Vol.114 (3), p.714-718 |
| issn | 0037-9727 1535-3702 1535-3699 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_83525913 |
| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Adrenalectomy Calcification, Physiologic Calcinosis Calcium Isotopes Desoxycorticosterone Hydrocortisone Kidney Myocardium Old Medline Parathyroid Glands Parathyroid Hormone Parathyroidectomy Physiology Rats Tissue Extracts |
| title | Enhancement of Metastatic Calcification Produced with Parathyroid Extract by Parathyroidectomy and Adrenalectomy |
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