Enhancement of Metastatic Calcification Produced with Parathyroid Extract by Parathyroidectomy and Adrenalectomy

Enhancement of Metastatic Calcification Produced with Parathyroid Extract by Parathyroidectomy and Adrenalectomy

Summary Groups of rats were injected with 150 units of bovine PTE over 28 hours. At the end of experiment they were injected intravenously with a standard dose of Ca45Cl2. The extent of the calcific changes was judged from von Kossa stained sections and from concentrations of Ca45/mg tissue. Strikin...

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Veröffentlicht in:Experimental biology and medicine (Maywood, N.J.) N.J.), 1963-12, Vol.114 (3), p.714-718
Hauptverfasser: Stoerk, Herbert C., Celozzi, Evemarie
Format: Artikel
Sprache:eng
Schlagworte:
Adrenalectomy
Calcification, Physiologic
Calcinosis
Calcium Isotopes
Desoxycorticosterone
Hydrocortisone
Kidney
Myocardium
Old Medline
Parathyroid Glands
Parathyroid Hormone
Parathyroidectomy
Physiology
Rats
Tissue Extracts
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Beschreibung
Zusammenfassung:Summary Groups of rats were injected with 150 units of bovine PTE over 28 hours. At the end of experiment they were injected intravenously with a standard dose of Ca45Cl2. The extent of the calcific changes was judged from von Kossa stained sections and from concentrations of Ca45/mg tissue. Striking enhancement of metastatic calcifications was observed in parathyroidectomized and in adrenalectomized rats. DOCA and hydrocortisone prevented the appearance of the calcific changes in adrenalectomized rats.
ISSN:0037-9727
1535-3702
1535-3699
DOI:10.3181/00379727-114-28778