Poliovirus Type 1: Neutralization by Papain-Digested Antibodies

Poliovirus Type 1: Neutralization by Papain-Digested Antibodies

Papain-digested rabbit antibody (Porter's fractions I and II) can neutralize poliovirus. Neutralizing capacity after digestion ranged from 35 to 45 percent of that of the undigested antibody. No definite dissociation of the antibody fragments from the virus was observed after the reaction mixtu...

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Veröffentlicht in:Science (American Association for the Advancement of Science) 1964-09, Vol.145 (3639), p.1447-1448
Hauptverfasser: Vogt, Arnold, Kopp, Rudolf, Maass, Günter, Reich, Leo
Format: Artikel
Sprache:eng
Schlagworte:
Antibodies
Antiserum
Bee venoms
Diet
Food
gamma-Globulins
Immunoelectrophoresis
Immunoglobulin fragments
Mice
Old Medline
Papain
Poliovirus
Venoms
Viruses
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Zusammenfassung:Papain-digested rabbit antibody (Porter's fractions I and II) can neutralize poliovirus. Neutralizing capacity after digestion ranged from 35 to 45 percent of that of the undigested antibody. No definite dissociation of the antibody fragments from the virus was observed after the reaction mixture had been diluted in a neutral medium.
ISSN:0036-8075
1095-9203
DOI:10.1126/science.145.3639.1447