Interpretation of Distribution Coefficients of p‐Alkylpyridines by a Modified Regular Solution Theory
The hypothetical hexadecane–octane distribution coefficients for the alkylpyridines were deduced from the corresponding oil–water distribution data. The values were analyzed by a modified regular solution theory. A good correlation was noted by including the Flory–Huggins entropy factor in the calcu...
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| Veröffentlicht in: | Journal of pharmaceutical sciences 1976-05, Vol.65 (5), p.743-745 |
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| container_end_page | 745 |
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| container_issue | 5 |
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| container_title | Journal of pharmaceutical sciences |
| container_volume | 65 |
| creator | Yeh, Kuang C. Higuchi, William I. |
| description | The hypothetical hexadecane–octane distribution coefficients for the alkylpyridines were deduced from the corresponding oil–water distribution data. The values were analyzed by a modified regular solution theory. A good correlation was noted by including the Flory–Huggins entropy factor in the calculation and by considering the deviation from the geometric mean assumption. |
| doi_str_mv | 10.1002/jps.2600650531 |
| format | Article |
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The values were analyzed by a modified regular solution theory. A good correlation was noted by including the Flory–Huggins entropy factor in the calculation and by considering the deviation from the geometric mean assumption.</description><identifier>ISSN: 0022-3549</identifier><identifier>EISSN: 1520-6017</identifier><identifier>DOI: 10.1002/jps.2600650531</identifier><identifier>PMID: 932948</identifier><language>eng</language><publisher>Washington: Elsevier Inc</publisher><subject>Alkylpyridines-distribution coefficients interpreted ; Alkylpyridines—distribution coefficients interpreted, modified regular solution theory ; Chemical Phenomena ; Chemistry ; Distribution coefficients-alkylpyridines ; Distribution coefficients—alkylpyridines, interpreted by modified regular solution theory ; Hydrocarbons ; interpreted by modified regular solution theory ; modified regular solution theory ; Oils ; Picolines ; Pyridines ; Solubility ; Water</subject><ispartof>Journal of pharmaceutical sciences, 1976-05, Vol.65 (5), p.743-745</ispartof><rights>1976 Wiley-Liss, Inc., A Wiley company</rights><rights>Copyright © 1976 Wiley‐Liss, Inc., A Wiley Company</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4261-a491f5958b4dba4e40bef1f86c043ac0bcb339602b3dc487411d5fff40571b063</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fjps.2600650531$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fjps.2600650531$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/932948$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Yeh, Kuang C.</creatorcontrib><creatorcontrib>Higuchi, William I.</creatorcontrib><title>Interpretation of Distribution Coefficients of p‐Alkylpyridines by a Modified Regular Solution Theory</title><title>Journal of pharmaceutical sciences</title><addtitle>J. Pharm. Sci</addtitle><description>The hypothetical hexadecane–octane distribution coefficients for the alkylpyridines were deduced from the corresponding oil–water distribution data. The values were analyzed by a modified regular solution theory. A good correlation was noted by including the Flory–Huggins entropy factor in the calculation and by considering the deviation from the geometric mean assumption.</description><subject>Alkylpyridines-distribution coefficients interpreted</subject><subject>Alkylpyridines—distribution coefficients interpreted, modified regular solution theory</subject><subject>Chemical Phenomena</subject><subject>Chemistry</subject><subject>Distribution coefficients-alkylpyridines</subject><subject>Distribution coefficients—alkylpyridines, interpreted by modified regular solution theory</subject><subject>Hydrocarbons</subject><subject>interpreted by modified regular solution theory</subject><subject>modified regular solution theory</subject><subject>Oils</subject><subject>Picolines</subject><subject>Pyridines</subject><subject>Solubility</subject><subject>Water</subject><issn>0022-3549</issn><issn>1520-6017</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1976</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkctu1DAUhi3EbRjYsmKRFbsMdmznsixTKL1wUaeIpeXLcXGbiYOdANn1EfqMfRI8pCpigVhZ1vn_zzqfEXpO8IpgXLy66OOqKDEuOeaU3EMLwgucl5hU99EiBYqcctY8Rk9ivMAphjl_hB42tGhYvUDnh90AoQ8wyMH5LvM223dxCE6Nv-9rD9Y67aAb4m7Y31xd77WXU9tPwRnXQczUlMnsvTfOOjDZKZyPrQzZxrcz4ewr-DA9RQ-sbCM8uz2X6PPbN2frd_nJx4PD9d5JrllRklyyhlje8FoxoyQDhhVYYutSY0alxkorSpsSF4oazeqKEWK4tZZhXhGFS7pEL2duH_y3EeIgti5qaFvZgR-jqClrGE-wJVrNQR18jAGs6IPbyjAJgsVOrEhixR-xqfDiljyqLZi7-GwyjZt5_MO1MP0HJo4-bf5C53M3mYefd10ZLkVZ0YqLLx8OBH19XG_Wp8fpwSWq5zwkk98dBBF3P6TBuAB6EMa7f23xC0grqKE</recordid><startdate>197605</startdate><enddate>197605</enddate><creator>Yeh, Kuang C.</creator><creator>Higuchi, William I.</creator><general>Elsevier Inc</general><general>Wiley Subscription Services, Inc., A Wiley Company</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>197605</creationdate><title>Interpretation of Distribution Coefficients of p‐Alkylpyridines by a Modified Regular Solution Theory</title><author>Yeh, Kuang C. ; Higuchi, William I.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4261-a491f5958b4dba4e40bef1f86c043ac0bcb339602b3dc487411d5fff40571b063</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1976</creationdate><topic>Alkylpyridines-distribution coefficients interpreted</topic><topic>Alkylpyridines—distribution coefficients interpreted, modified regular solution theory</topic><topic>Chemical Phenomena</topic><topic>Chemistry</topic><topic>Distribution coefficients-alkylpyridines</topic><topic>Distribution coefficients—alkylpyridines, interpreted by modified regular solution theory</topic><topic>Hydrocarbons</topic><topic>interpreted by modified regular solution theory</topic><topic>modified regular solution theory</topic><topic>Oils</topic><topic>Picolines</topic><topic>Pyridines</topic><topic>Solubility</topic><topic>Water</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Yeh, Kuang C.</creatorcontrib><creatorcontrib>Higuchi, William I.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of pharmaceutical sciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Yeh, Kuang C.</au><au>Higuchi, William I.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Interpretation of Distribution Coefficients of p‐Alkylpyridines by a Modified Regular Solution Theory</atitle><jtitle>Journal of pharmaceutical sciences</jtitle><addtitle>J. Pharm. Sci</addtitle><date>1976-05</date><risdate>1976</risdate><volume>65</volume><issue>5</issue><spage>743</spage><epage>745</epage><pages>743-745</pages><issn>0022-3549</issn><eissn>1520-6017</eissn><abstract>The hypothetical hexadecane–octane distribution coefficients for the alkylpyridines were deduced from the corresponding oil–water distribution data. The values were analyzed by a modified regular solution theory. A good correlation was noted by including the Flory–Huggins entropy factor in the calculation and by considering the deviation from the geometric mean assumption.</abstract><cop>Washington</cop><pub>Elsevier Inc</pub><pmid>932948</pmid><doi>10.1002/jps.2600650531</doi><tpages>3</tpages></addata></record> |
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| ispartof | Journal of pharmaceutical sciences, 1976-05, Vol.65 (5), p.743-745 |
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| language | eng |
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| source | MEDLINE; Access via Wiley Online Library; Alma/SFX Local Collection |
| subjects | Alkylpyridines-distribution coefficients interpreted Alkylpyridines—distribution coefficients interpreted, modified regular solution theory Chemical Phenomena Chemistry Distribution coefficients-alkylpyridines Distribution coefficients—alkylpyridines, interpreted by modified regular solution theory Hydrocarbons interpreted by modified regular solution theory modified regular solution theory Oils Picolines Pyridines Solubility Water |
| title | Interpretation of Distribution Coefficients of p‐Alkylpyridines by a Modified Regular Solution Theory |
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