On the structure of coated vesicles

On the structure of coated vesicles

Electron micrographs of tilted specimens of coated vesicles show that their coats are based on polyhedral lattices constructed from 12 pentagons plus a variable number of hexagons. We have identified three such structures among the smaller particles, two containing 108 molecules of clathrin and a th...

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Veröffentlicht in:Journal of molecular biology 1976-06, Vol.103 (4), p.785-798
Hauptverfasser: Crowther, R.A., Pinch, J.T., Pearse, B.M.F.
Format: Artikel
Sprache:eng
Schlagworte:
Adrenal Medulla - ultrastructure
Animals
Brain - ultrastructure
Cattle
Humans
Microscopy, Electron
Models, Structural
Organ Specificity
Organoids - ultrastructure
Swine
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Zusammenfassung:Electron micrographs of tilted specimens of coated vesicles show that their coats are based on polyhedral lattices constructed from 12 pentagons plus a variable number of hexagons. We have identified three such structures among the smaller particles, two containing 108 molecules of clathrin and a third containing 84. The coats of larger particles are believed to be constructed on similar principles. This polymorphism enables a variety of vesicles to be accommodated in an economical manner.
ISSN:0022-2836
1089-8638
DOI:10.1016/0022-2836(76)90209-6