Differences in Serum Complement Activity among Inbred Strains of Mice

Differences in Serum Complement Activity among Inbred Strains of Mice

Variation in complement activity among inbred strains of mice has been confirmed. In addition, evidence is presented that sera from Balb/cAnN, C57BL/10ScN, B10·D2/Sn “new,” B10·D2/Sn “old,” DBA/2JN and C57BL/6JN have C′1, C′4 and C′2 activities and that differences in C′ titer, in part, may be due t...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:The Journal of immunology (1950) 1964-04, Vol.92 (4), p.576-578
Hauptverfasser: Terry, William D, Borsos, Tibor, Rapp, Herbert J
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Antibodies
Complement System Proteins
Erythrocytes
Genetics
Hemolysis
Immune Sera
Mice
Mice, Inbred Strains
Old Medline
Sex
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Variation in complement activity among inbred strains of mice has been confirmed. In addition, evidence is presented that sera from Balb/cAnN, C57BL/10ScN, B10·D2/Sn “new,” B10·D2/Sn “old,” DBA/2JN and C57BL/6JN have C′1, C′4 and C′2 activities and that differences in C′ titer, in part, may be due to variation in C′3 complex activity. Sera from Balb/cAnN, C57BL/10ScN, and B10·D2/Sn “new” males contain significantly greater C′ and C′3 complex activity than sera from females of the same strain.
ISSN:0022-1767
1550-6606
DOI:10.4049/jimmunol.92.4.576