COLD ADAPTATION AND THE ANAESTHETIC REQUIREMENT FOR CYCLOPROPANE IN RATS

COLD ADAPTATION AND THE ANAESTHETIC REQUIREMENT FOR CYCLOPROPANE IN RATS

The effect of cold adaptation at 4 °C on cyclopropane MAC was studied in 10 Wistar rats over a 16-week period. Compared with a similar control group (normally adapted), there was a significant decrease in weight gain and a significant increase in anaesthetic requirement in the cold-adapted rats.

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Veröffentlicht in:British journal of anaesthesia : BJA 1976-06, Vol.48 (6), p.509-512
Hauptverfasser: REITAN, J.A., AINSLIE, S.T., MARTUCCI, R.W., ILLEMAN, M.L.
Format: Artikel
Sprache:eng
Schlagworte:
Adaptation, Physiological
Anesthesia, Inhalation - methods
Animals
Body Temperature
Body Weight
Cold Temperature
Cyclopropanes
Dose-Response Relationship, Drug
Rats
Rats, Inbred Strains
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Zusammenfassung:The effect of cold adaptation at 4 °C on cyclopropane MAC was studied in 10 Wistar rats over a 16-week period. Compared with a similar control group (normally adapted), there was a significant decrease in weight gain and a significant increase in anaesthetic requirement in the cold-adapted rats.
ISSN:0007-0912
1471-6771
DOI:10.1093/bja/48.6.509